Bus Tickets from Frankfurt am Main to Pisa

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TodayJun 3
from $100
TomorrowJun 4
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TueJun 10

Next departures to Pisa

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 3 at
    Departure city: Frankfurt am Main
    Departure location: Frankfurt Hbf
    Arrival time: June 4 at
    Destination city: Pisa
    Destination location: Parcheggio Via Pietransantina
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 3 at
    Departure city: Frankfurt am Main
    Departure location: FRA Frankfurt airport
    Arrival time: June 4 at
    Destination city: Pisa
    Destination location: Parcheggio Via Pietransantina
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: June 3 at
    Departure city: Frankfurt am Main
    Departure location: FRA Frankfurt airport
    Arrival time: June 4 at
    Destination city: Pisa
    Destination location: Parcheggio Via Pietransantina
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: June 3 at
    Departure city: Frankfurt am Main
    Departure location: Südbahnhof
    Arrival time: June 4 at
    Destination city: Pisa
    Destination location: Parcheggio Via Pietransantina
    Operated by: Flixtrain + Flixbus
    Flixtrain + Flixbus
    Vehicle: BusDuration:
  • Departure time: June 3 at
    Departure city: Frankfurt am Main
    Departure location: FRA Frankfurt airport
    Arrival time: June 4 at
    Destination city: Pisa
    Destination location: Parcheggio Via Pietransantina
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Accepted payments

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Compare 3 ways to go from Frankfurt am Main to Pisa.

Bus
Average Price$100 - $226Average Duration21h 40m
18kg CO₂e5 out of 5 stars
Train
Average Price$107 - $226Average Duration22h 18m
17kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average Price$82 - $82Average Duration11h
30kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Frankfurt am Main to Pisa

Among the sustainable travel choices, the carpool stands out as the good way to reach Pisa. The journey takes about 11 hours and with fares starting at just $82, it presents an excellent value for a comfortable ride.

1carpool per day
11hAverage Duration
$82Cheapest ticket
30kgCO₂ emissions

Bus Frankfurt am Main to Pisa: Trip Overview

Average ticket price$124
Average bus trip duration21h 40m
Number of daily buses7
Earliest bus departure12:45am
Distance448 miles (721 km)
Latest bus departure11:05pm

Frankfurt am Main to Pisa Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Frankfurt am Main to Pisa.

Bus service from Frankfurt am Main to Pisa will be provided by the most trusted bus companies.

Discover how much the bus trip from Frankfurt am Main to Pisa will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Frankfurt am Main - Pisa

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/01
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Today
$93
06/04
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busbud logoThe cheapest trip from Frankfurt am Main to Pisa was searched and found on Jun 3, 2025 with a price of $93

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Pisa, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Frankfurt am Main to Pisa but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Frankfurt am Main to Pisa, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Frankfurt am Main to Pisa will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Frankfurt am Main to Pisa, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Frankfurt am Main by bus?

Bus from Frankfurt am Main to Pisa

You can also go to Pisa by train

Train from Frankfurt am Main to Pisa

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