Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Florenc | P+R Bouillon | CheapestFastest |
Last refresh of the prices: Last Tuesday at 11:36 AM CET.
Compare 2 ways to go from Prague to Luxembourg
Among the sustainable travel choices, the bus stands out as the good way to reach Luxembourg. The journey takes about 15 hours 10 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Luxembourg?
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- EChlumecká, 198 00 Praha 20, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Luxembourg
- A
Luxembourg
3 Rue Genistre, 1623 Luxembourg, Luxembourg - B
Luxembourg Central Station
Place de la Gare 13, 1616 Luxembourg - C
Luxembourg Kirchberg
Rue Alphonse Weicker 4, 2721 Luxemburg, Luxemburg - D
Rue du Commerce
Rue du Commerce, 1351 Luxembourg, Luxembourg
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Frequently asked questions about traveling from Prague to Luxembourg by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Prague to Luxembourg?
The cheapest bus tickets from Prague to Luxembourg start from $44. The average price for this route is around $68. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Luxembourg?
The average bus trip duration from Prague to Luxembourg is 15h 10m, covering a distance of 372 miles (600 km). The quickest bus can get you there in 9h 10m and is operated by RegioJet.
Which bus companies service the Prague to Luxembourg route?
Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Prague to Luxembourg?
The earliest bus departs from Prague to Luxembourg at 3:30am. And the latest bus departs at 11:05pm.
What are the CO₂ emissions for the bus trip from Prague to Luxembourg?
A bus trip from Prague to Luxembourg generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Prague to Luxembourg?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1057 reviews.
Which bus company has the best Wi-Fi from Prague to Luxembourg?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Prague to Luxembourg?
According to Busbud traveller reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Prague to Luxembourg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Luxembourg was searched and found on Nov 28, 2025 with a price of $59To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Luxembourg, as early as possible.
You can expect to pay from $59 to $59 for a bus ticket from Prague to Luxembourg based on the last 2 days. You can expect to find the cheapest price for the trip at $59 which is on 2025-12-02.
What's the cheapest way to go from Prague to Luxembourg?
The bus is the cheapest travel choice for this destination