Next available departures

Next departures for Prague to Luxembourg on October 19
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Ceske Drahy + DB Regio Südost + Deutsche Bahn + CFL	6:47pm	Hlavní nádraží	14h 53m	9:40am	Luxembourg Train Station	CheapestFastest
Ceske Drahy + DB Regio Südost + Deutsche Bahn + CFL	6:47pm	Hlavní nádraží	14h 53m	9:40am	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Südost + Deutsche Bahn + CFL	6:47pm	Hlavní nádraží	14h 53m	9:40am	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Südost + Deutsche Bahn + CFL	6:47pm	Hlavní nádraží	14h 53m	9:40am	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Südost + Deutsche Bahn + CFL	6:47pm	Hlavní nádraží	14h 53m	9:40am	Luxembourg Train Station	No tags

Next departures for Prague to Luxembourg on October 20
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Toilet Power outlets	6:00pm	Florenc	9h 10m	3:10am	P+R Bouillon	CheapestFastest
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL		6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Westfrankenbahn + DB Regio Baden-Württemberg + SÜWEX + CFL		7:35am	Hlavní nádraží	12h 15m	7:50pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL		6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Westfrankenbahn + DB Regio Baden-Württemberg + SÜWEX + CFL		7:35am	Hlavní nádraží	12h 15m	7:50pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL		6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Westfrankenbahn + DB Regio Baden-Württemberg + SÜWEX + CFL		1:35pm	Hlavní nádraží	17h 25m	7:00am	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL		6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags

Next departures for Prague to Luxembourg on October 21
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Deutsche Bahn + SÜWEX + CFL	7:35am	Hlavní nádraží	13h 15m	8:50pm	Luxembourg Train Station	Cheapest
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	8:31am	Hlavní nádraží	11h 19m	7:50pm	Luxembourg Train Station	Fastest
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Westfrankenbahn + DB Regio Baden-Württemberg + SÜWEX + CFL	7:35am	Hlavní nádraží	12h 15m	7:50pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Westfrankenbahn + DB Regio Baden-Württemberg + SÜWEX + CFL	7:35am	Hlavní nádraží	12h 15m	7:50pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Westfrankenbahn + DB Regio Baden-Württemberg + SÜWEX + CFL	1:35pm	Hlavní nádraží	17h 25m	7:00am	Luxembourg Train Station	No tags

Next departures for Prague to Luxembourg on October 22
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Deutsche Bahn + SÜWEX + CFL	7:35am	Hlavní nádraží	13h 15m	8:50pm	Luxembourg Train Station	Cheapest
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	8:31am	Hlavní nádraží	11h 19m	7:50pm	Luxembourg Train Station	Fastest
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Westfrankenbahn + DB Regio Baden-Württemberg + SÜWEX + CFL	7:35am	Hlavní nádraží	12h 15m	7:50pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Westfrankenbahn + DB Regio Baden-Württemberg + SÜWEX + CFL	7:35am	Hlavní nádraží	12h 15m	7:50pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags

Next departures for Prague to Luxembourg on October 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Toilet Power outlets	6:00pm	Florenc	9h 10m	3:10am	P+R Bouillon	CheapestFastest
Ceske Drahy + Deutsche Bahn + CFL		12:31pm	Hlavní nádraží	11h 19m	11:50pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + CFL		12:31pm	Hlavní nádraží	11h 19m	11:50pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + CFL		12:31pm	Hlavní nádraží	11h 19m	11:50pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + DB Regio Mitte + CFL		3:35pm	Hlavní nádraží	15h 25m	7:00am	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + DB Regio Mitte + CFL		3:35pm	Hlavní nádraží	15h 25m	7:00am	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + DB Regio Mitte + CFL		6:31pm	Hlavní nádraží	14h 9m	8:40am	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + DB Regio Mitte + CFL		6:31pm	Hlavní nádraží	14h 9m	8:40am	Luxembourg Train Station	No tags

Next departures for Prague to Luxembourg on October 24
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Ceske Drahy + DB Regio Bayern + Go-Ahead Baden-Württemberg + Deutsche Bahn + SÜWEX + CFL	7:35am	Hlavní nádraží	13h 15m	8:50pm	Luxembourg Train Station	Cheapest
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	8:31am	Hlavní nádraží	11h 19m	7:50pm	Luxembourg Train Station	Fastest
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Südost + Deutsche Bahn + CFL	8:47am	Hlavní nádraží	12h 3m	8:50pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Südost + Deutsche Bahn + CFL	8:47am	Hlavní nádraží	12h 3m	8:50pm	Luxembourg Train Station	No tags
Ceske Drahy + Deutsche Bahn + SÜWEX + CFL	6:31am	Hlavní nádraží	11h 34m	6:05pm	Luxembourg Train Station	No tags
Ceske Drahy + DB Regio Südost + Deutsche Bahn + CFL	8:47am	Hlavní nádraží	12h 3m	8:50pm	Luxembourg Train Station	No tags

Last refresh of the prices: Last Thursday at 10:47 AM CEST.

Compare 2 ways to go from Prague to Luxembourg

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Luxembourg. The journey takes about 14 hours 25 minutes, and with fares starting at just $54, it presents an excellent value for a comfortable ride.

4bus per day

14h 25mAverage Duration

597 kmDistance

15kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$54 - $171	Average Duration14h 25m	CO₂ emissions 15kg CO₂e
Train	Average Price$90 - $456	Average Duration12h 52m	CO₂ emissions 14kg CO₂e

Bus stations and stops in Prague and Luxembourg

Stops in Prague

A
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page
B
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
C
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page
D
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page
E
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Stops in Luxembourg

A
Luxembourg
3 Rue Genistre, 1623 Luxembourg, Luxembourg
B
Luxembourg Central Station
Place de la Gare 13, 1616 Luxembourg
C
Luxembourg Kirchberg
Rue Alphonse Weicker 4, 2721 Luxemburg, Luxemburg
D
Rue du Commerce
Rue du Commerce, 1351 Luxembourg, Luxembourg

Compare companies

FlixBus

3.5/516,305 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

RegioJet

4.1/51,116 reviews

Staff4.5

Timeliness4.0

Cleanliness4.3

Wi‑Fi3.7

LU bus companies:FlixBus, BlaBlaCar Bus, Deutsche Bahn, Sindbad, Ecolines, KLR Bus, RegioJet

Frequently asked questions about travelling from Prague to Luxembourg by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Prague to Luxembourg?
The cheapest bus tickets from Prague to Luxembourg start from $54. The average price for this route is around $88. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Luxembourg?
The average bus travel time from Prague to Luxembourg is 14h 25m, covering a distance of 597 km. The quickest bus can get you there in 9h 10m and is operated by RegioJet.
Which bus companies service the Prague to Luxembourg route?
Several major bus companies operate on this route with 4 buses available per day, including services from FlixBus, RegioJet.
What are the earliest and latest departure times for the bus from Prague to Luxembourg?
The earliest bus departs from Prague to Luxembourg at 7:55am. And the latest bus departs at 11:05pm.
What are the CO₂ emissions for the bus trip from Prague to Luxembourg?
A bus trip from Prague to Luxembourg generates an estimated 14.918025 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Prague to Luxembourg?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1116 reviews.
Which bus company has the best Wi-Fi from Prague to Luxembourg?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.7.
Which bus company has the best on-time performance from Prague to Luxembourg?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Luxembourg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

10-17

No data

10-18

$101

Today

No data

10-20

$84

10-21

No data

10-22

No data

10-23

$100

10-24

No data

The cheapest trip from Prague to Luxembourg was searched and found on Oct 20, 2026 with a price of $84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Luxembourg, as early as possible.

You can expect to pay from $84 to $278 for a bus ticket from Prague to Luxembourg based on the last 2 days. You can expect to find the cheapest price for the trip at $84 which is on 2026-10-20.