Train from Florence, SC, US to Boston, MA, US: Tickets & Schedules

Next train departures

Next departures for Florence to Boston on March 19
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Florence Station
South Station (Train Terminal)Cheapest
AmtrakTrain
Florence Station
Boston Route 128, MAFastest
AmtrakTrain
Florence Station
South Station (Train Terminal)No tags
AmtrakTrain
Florence Station
Boston Route 128, MANo tags
AmtrakTrain
Florence Station
Back Bay StationNo tags

Last refresh of the prices: Yesterday at 1:49 PM EDT.

Compare 2 ways to go from Florence to Boston

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Boston. The journey takes about 1 day, 2 hours 50 minutes and with fares starting at just $85, it presents an excellent value for a comfortable ride.

4bus per day
1d 2hAverage Duration
734 milesDistance
30kgCO₂ emissions
Average Price$85 - $266Average Duration1d 2h
30kg CO₂e
Average Price$138 - $543Average Duration20h 32m
106kg CO₂e

Frequently asked questions about traveling from Florence, SC, US to Boston, MA, US by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Florence to Boston?

    The cheapest train tickets from Florence to Boston start from $138. The average price for this train route is around $292. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the train journey from Florence to Boston?

    The average train ride duration from Florence to Boston is 20h 32m, covering a distance of 723 miles (1165 km). The quickest train can get you there in 18h 32m and is operated by Amtrak.

  3. Which train operators service the Florence to Boston route?

    Several major train operators operate on this route with 6 trains available per day.

  4. What is the earliest and latest departure time for the train from Florence to Boston?

    The earliest train departs from Florence to Boston at 10:54am. And the latest train departs at 10:32pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/17
$136
03/18
$157
Today
$398
03/20
$132
03/21
No data
03/22
No data
03/23
No data
03/24
No data
busbud logoThe cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Mar 20, 2026 with a price of $132

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Boston, MA, US, as early as possible.

You can expect to pay from $132 to $725 for a train ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $132 which is on 2026-03-20.

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