Previously seen trips

Next departures for Florence to Boston on September 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
FlixBus + Greyhound	Bus	12:05am	Florence, SC	18h 45m	6:50pm	Boston (South Station)
Greyhound + FlixBus	Bus	12:05am	Florence, SC	18h 45m	6:50pm	Boston (South Station)
Greyhound + FlixBus	Bus	12:05am	Florence, SC	1d 5h	5:40am	Brookline
FlixBus + Greyhound	Bus	12:05am	Florence, SC	1d 5h	5:40am	Brookline
FlixBus + Greyhound	Bus	5:45am	Florence, SC	1d 9h	3:10pm	Boston (South Station)

Compare 2 ways to go from Florence to Boston

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Boston. The journey takes about 1 day and with fares starting at just CLP 74,854, it presents an excellent value for a comfortable ride.

8bus per day

1d Average Duration

733 milesDistance

30kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCLP 74,854 - CLP 351,690	Average Duration1d	CO₂ emissions 30kg CO₂e
Train	Average PriceCLP 143,932 - CLP 603,975	Average Duration20h 32m	CO₂ emissions 107kg CO₂e

Bus stations and stops in Florence and Boston

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Boston

A
Back Bay Station
145 Dartmouth St, Boston, MA 02116, USA
Visit page
B
North Station
100 Legends Way, Boston, MA 02114, USA
Visit page
C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA
D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA
E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA
F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA

Compare bus companies

FlixBus

3.5/515,567 reviews

Staff4.1

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/588,130 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, Greyhound, Futura, Chihuahuenses, Tufesa, Adirondack Trailways, Valley Transit

Frequently asked questions about traveling from Florence, SC, US to Boston, MA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Florence to Boston?
The cheapest bus tickets from Florence to Boston start from CLP 74,854. The average price for this route is around CLP 103,583. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Boston?
The average bus trip duration from Florence to Boston is 1d , covering a distance of 733 miles (1181 km). The quickest bus can get you there in 19h 15m and is operated by FlixBus.
Which bus companies service the Florence to Boston route?
Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Florence to Boston?
The earliest bus departs from Florence to Boston at 12:05am. And the latest bus departs at 7:20pm.
What are the CO₂ emissions for the bus trip from Florence to Boston?
A bus trip from Florence to Boston generates an estimated 29.522725 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Boston?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 15390 reviews.
Which bus company has the best Wi-Fi from Florence to Boston?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Florence to Boston?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Florence to Boston?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/06

CLP 158,033

09/07

CLP 235,626

Today

CLP 91,455

09/09

No data

09/10

CLP 100,556

09/11

CLP 109,656

09/12

CLP 114,446

09/13

CLP 108,698

The cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Sep 8, 2026 with a price of CLP 91,455

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US, as early as possible.

You can expect to pay from CLP 91,455 to CLP 344,822 for a bus ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 100,556 which is on 2026-09-10.