How much is the train ticket from Florence to Harrisburg?

The cheapest train tickets from Florence to Harrisburg start from $179. The average price for this train route is around $244. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the train journey from Florence to Harrisburg?

The average train ride duration from Florence to Harrisburg is 13h 15m, covering a distance of 447 miles (721 km). The quickest train can get you there in 13h 13m and is operated by Amtrak .

Which train operators service the Florence to Harrisburg route?

Several major train operators operate on this route with 1 trains available per day.

What is the earliest and latest departure time for the train from Florence to Harrisburg?

The earliest train departs from Florence to Harrisburg at 11:32pm. And the latest train departs at 11:32pm.

Train Florence to Harrisburg from $179 | Refundable Tickets

Previously seen trips

Next departures for Florence to Harrisburg on December 31
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	11:32pm	Florence Station	13h 15m	12:47pm	Harrisburg, PA	No tags
Train	11:32pm	Florence Station	13h 10m	12:42pm	Harrisburg, PA	No tags
Train	11:32pm	Florence Station	13h 10m	12:42pm	Harrisburg, PA	No tags
Train	11:32pm	Florence Station	13h 13m	12:45pm	Harrisburg, PA	No tags
Train	11:32pm	Florence Station	13h 15m	12:47pm	Harrisburg, PA	No tags

Compare 2 ways to go from Florence to Harrisburg

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Harrisburg. The journey takes about 13 hours 15 minutes and with fares starting at just $179, it presents an excellent value for a comfortable ride.

1train per day

13h 15mAverage Duration

447 milesDistance

66kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$122 - $281	Average Duration21h 25m	CO₂ emissions 18kg CO₂e
Train	Average Price$179 - $1,315	Average Duration13h 15m	CO₂ emissions 66kg CO₂e

Train Companies

Amtrak

4/55,690 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Based on 5690 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $179

Train and bus companies in US:Amtrak, Trenitalia, Renfe, VIA Rail Canada, Amtrak Acela, NS Nederlandse Spoorwegen, Iryo

Frequently asked questions about traveling from Florence, SC, US to Harrisburg by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Florence to Harrisburg?
The cheapest train tickets from Florence to Harrisburg start from $179. The average price for this train route is around $244. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Florence to Harrisburg?
The average train ride duration from Florence to Harrisburg is 13h 15m, covering a distance of 447 miles (721 km). The quickest train can get you there in 13h 13m and is operated by Amtrak.
Which train operators service the Florence to Harrisburg route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Florence to Harrisburg?
The earliest train departs from Florence to Harrisburg at 11:32pm. And the latest train departs at 11:32pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/29

$340

12/30

$237

Today

No data

The cheapest trip from Florence, SC, US to Harrisburg was searched and found on Dec 30, 2025 with a price of $237

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Harrisburg, as early as possible.