Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Florence Station | Harrisburg, PA | No tags | ||||
| Train | Florence Station | Harrisburg, PA | No tags | ||||
| Train | Florence Station | Harrisburg, PA | No tags | ||||
| Train | Florence Station | Harrisburg, PA | No tags | ||||
| Train | Florence Station | Harrisburg, PA | No tags |
Compare 2 ways to go from Florence to Harrisburg
Among the sustainable travel choices, the train stands out as a good way to reach Harrisburg. The journey takes about 13 hours 15 minutes, and with fares starting at just $251, it presents an excellent value for a comfortable ride.
Train companies
Based on 5690 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $251
Frequently asked questions about travelling from Florence, SC, US to Harrisburg by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Florence to Harrisburg?
The cheapest train tickets from Florence to Harrisburg start at $251. The average price for this train route is around $342. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Florence to Harrisburg?
The average train trip from Florence to Harrisburg takes 13h 15m and covers 721 km. The quickest train gets you there in 13h 13m and is operated by Amtrak.
Which train operators serve the Florence to Harrisburg route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Florence to Harrisburg?
The earliest train from Florence to Harrisburg departs at 11:32pm. The latest train departs at 11:32pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Harrisburg was searched and found on Dec 30, 2025 with a price of $333To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Harrisburg, as early as possible.
