Trains tickets from Durham, NC, US to Buffalo, NY

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TodayJun 29
TomorrowJun 30
TueJul 1
from $277
WedJul 2
ThuJul 3
FriJul 4
SatJul 5
SunJul 6

Trains leaving Tuesday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: July 1 at
    Departure city: Durham
    Departure location: Durham Station
    Arrival time: July 2 at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: July 1 at
    Departure city: Durham
    Departure location: Durham Station
    Arrival time: July 2 at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: July 1 at
    Departure city: Durham
    Departure location: Durham Station
    Arrival time: July 2 at
    Destination city: Buffalo
    Destination location: Exchange Street Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: July 1 at
    Departure city: Durham
    Departure location: Durham Station
    Arrival time: July 2 at
    Destination city: Buffalo
    Destination location: Exchange Street Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

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Compare 2 ways to go from Durham to Buffalo.

Bus
Average Price$88 - $278Average Duration21h 40m
19kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$176 - $388Average Duration1d 6h
70kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Durham to Buffalo

Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 21 hours 40 minutes and with fares starting at just $88, it presents an excellent value for a comfortable ride.

11bus per day
21h 40mAverage Duration
$88Cheapest ticket
19kgCO₂ emissions

Train Durham to Buffalo: Trip Overview

Please note, this information is subject to change.

Average ticket price$340
Average train trip duration1d 6h
Number of daily trains2
Earliest train departure9:27am
Distance477 miles (768 km)

Durham to Buffalo Train

With Busbud, comparing and booking tickets for a train from Durham to Buffalo is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.

Train service from Durham to Buffalo will be provided by the most trusted companies.

Discover how much the train trip from Durham to Buffalo will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.

Frequently asked questions for your trip Durham, NC, US - Buffalo, NY

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/27
No data
06/28
$327
Today
No data
06/30
No data
07/01
$266
07/02
No data
07/03
No data
07/04
No data
busbud logoThe cheapest trip from Durham to Buffalo was searched and found on Jul 1, 2025 with a price of $266

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Durham to Buffalo, as early as possible.

You can expect to pay from $266 to $385 for a train ticket from Durham to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at $266 which is on 2025-07-01.

About Train Travel

Train Travel Tips

Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Durham to Buffalo is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.

No matter if you plan to take a regional or high-speed train to Buffalo, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.

With up to 30x less CO2 emissions for your train journey between Durham and Buffalo, the train is an ecological alternative to flights or personal cars.

Make a music playlist for your train ride from Durham to Buffalo, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Railway companies played a major role as early as 1883 in the use of time zones as we know them today.

The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers traveled aboard the Shinkansen at a speed of 210 km / h.

The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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