Trains tickets from Jacksonville (FL) to Greenville (SC)

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TodayMay 15
TomorrowMay 16
from $435
SatMay 17
SunMay 18
MonMay 19
TueMay 20
WedMay 21
ThuMay 22

Trains leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: May 16 at
    Departure city: Jacksonville
    Departure location: Jacksonville Amtrak Station
    Arrival time: May 18 at
    Destination city: Greenville
    Destination location: Greenville Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: May 16 at
    Departure city: Jacksonville
    Departure location: Jacksonville Amtrak Station
    Arrival time: May 18 at
    Destination city: Greenville
    Destination location: Greenville Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

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Compare 2 ways to go from Jacksonville to Greenville.

Bus
Average Price$64 - $159Average Duration11h 20m
13kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$145 - $616Average Duration1d 12h
46kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to Greenville

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 11 hours 20 minutes and with fares starting at just $64, it presents an excellent value for a comfortable ride.

2bus per day
11h 20mAverage Duration
$64Cheapest ticket
13kgCO₂ emissions

Train Jacksonville to Greenville: Trip Overview

Please note, this information is subject to change.

Average ticket price$288
Average train trip duration1d 12h
Number of daily trains1
Earliest train departure5:11pm
Distance313 miles (504 km)
Latest train departure10:29pm

Jacksonville to Greenville Train

Busbud shows you the best train ticket fares and train schedules so you can easily plan and book a trip by train from Jacksonville to Greenville.

We make sure you can find a train service from Jacksonville to Greenville from the most reliable train companies operating this trip.

Whether it is train tickets or first class train tickets going to Greenville from Jacksonville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Jacksonville - Greenville

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/13
No data
05/14
No data
Today
No data
05/16
$435
05/17
No data
05/18
No data
05/19
No data
05/20
No data
busbud logoThe cheapest trip from Jacksonville to Greenville was searched and found on May 16, 2025 with a price of $435

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jacksonville to Greenville, as early as possible.

You can expect to pay from $435 to $959 for a train ticket from Jacksonville to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at $435 which is on 2025-05-16.

About Train Travel

Train Travel Tips

Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between Jacksonville and Greenville is also a great way to travel to arrive in the city centre and save more time for your stay in Greenville.

Regional train? High-speed train? Whichever train to Greenville you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

By choosing the train between Jacksonville and Greenville, you emit up to 30 times less CO2 than for the same journey made by plane or car!

Tune out to the fine sounds of your best music playlist on your train trip from Jacksonville to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.

The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date

Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.

Will you be returning to Jacksonville by train?

Train from Greenville to Jacksonville

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