Trains leaving Friday
One passenger / one way
- This trip is recommended because it is: Cheapest + FastestDeparture time: August 22 atDeparture city: LancasterDeparture location: Lancaster, PAArrival time: August 22 atDestination city: CharlestonDestination location: Charleston StationOperated by: Amtrak
Vehicle: TrainDuration: - Departure time: August 22 atDeparture city: LancasterDeparture location: Lancaster, PAArrival time: August 22 atDestination city: CharlestonDestination location: Charleston StationOperated by: AmtrakVehicle: TrainDuration:
- Departure time: August 22 atDeparture city: LancasterDeparture location: Lancaster, PAArrival time: August 23 atDestination city: CharlestonDestination location: Charleston StationOperated by: AmtrakVehicle: TrainDuration:
- Departure time: August 22 atDeparture city: LancasterDeparture location: Lancaster, PAArrival time: August 23 atDestination city: CharlestonDestination location: Charleston StationOperated by: AmtrakVehicle: TrainDuration:
- Departure time: August 22 atDeparture city: LancasterDeparture location: Lancaster, PAArrival time: August 23 atDestination city: CharlestonDestination location: Charleston StationOperated by: AmtrakVehicle: TrainDuration:
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Train Lancaster, PA, US to Charleston, SC, US: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5406 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $150
Lancaster to Charleston Train
Busbud shows you the best train ticket fares and train schedules so you can easily plan and book a trip by train from Lancaster to Charleston.
We make it our job to connect you with the most dependable companies that offer train service from Lancaster to Charleston.
From train tickets to high-end trains trip from Lancaster to Charleston, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Lancaster, PA, US - Charleston, SC, US
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lancaster, PA, US to Charleston, SC, US was searched and found on Aug 23, 2025 with a price of $143To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Lancaster, PA, US to Charleston, SC, US, as early as possible.
You can expect to pay from $143 to $613 for a train ticket from Lancaster, PA, US to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $143 which is on 2025-08-23.
About Train Travel
Train Travel Tips
Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between Lancaster and Charleston is also a great way to travel to arrive in the city centre and save more time for your stay in Charleston.
Whether you take a regional or high-speed train to Charleston, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
The train emits up to 30x less CO2 for a trip between Lancaster and Charleston compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from Lancaster to Charleston.
Did you know?
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
One of the deepest train stations in the world is in Kiev. Located at a depth of 105 m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60 m under the Great Wall of China!
Top Traveled Train Routes
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Popular Trains Connecting Lancaster
Trains Leaving from Lancaster
Popular Trains Connecting Charleston
Trains Going to Charleston
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