Train from Pittsburgh to Florence, SC, US: Tickets & Schedules

Previously seen trips

Next departures for Pittsburgh to Florence on December 18
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Union Station
Florence StationNo tags
AmtrakTrain
Union Station
Florence StationNo tags
AmtrakTrain
Union Station
Florence StationNo tags
AmtrakTrain
Union Station
Florence StationNo tags
AmtrakTrain
Union Station
Florence StationNo tags

Compare 2 ways to go from Pittsburgh to Florence

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 14 hours 45 minutes and with fares starting at just $141, it presents an excellent value for a comfortable ride.

1bus per day
14h 45mAverage Duration
432 milesDistance
17kgCO₂ emissions
Average Price$141 - $344Average Duration14h 45m
17kg CO₂e
Average Price$207 - $1,481Average Duration21h 45m
63kg CO₂e

Frequently asked questions about traveling from Pittsburgh to Florence, SC, US by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the train ticket from Pittsburgh to Florence?

    The cheapest train tickets from Pittsburgh to Florence start from $207. The average price for this train route is around $294. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the train journey from Pittsburgh to Florence?

    The average train ride duration from Pittsburgh to Florence is 21h 45m, covering a distance of 431 miles (695 km). The quickest train can get you there in 19h 40m and is operated by Amtrak.

  3. Which train operators service the Pittsburgh to Florence route?

    Several major train operators operate on this route with 1 trains available per day.

  4. What is the earliest and latest departure time for the train from Pittsburgh to Florence?

    The earliest train departs from Pittsburgh to Florence at 5:25am. And the latest train departs at 7:30am.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/15
No data
12/16
$214
Today
$277
12/18
No data
12/19
No data
12/20
No data
12/21
No data
12/22
No data
busbud logoThe cheapest trip from Pittsburgh to Florence, SC, US was searched and found on Dec 16, 2025 with a price of $214

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Pittsburgh to Florence, SC, US, as early as possible.

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