Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Hotelu Grand | Heysel | Cheapest | |||||
| Hotelu Grand | Brussels South (Gare du Midi) | Fastest | |||||
| Hotelu Grand | Brussels Airport BRU (Parking P14) | No tags | |||||
| Hotelu Grand | Brussels Airport BRU (Parking P14) | No tags | |||||
| Hotelu Grand | Brussels Airport BRU (Parking P14) | No tags | |||||
| Hotelu Grand | Brussels Airport BRU (Parking P14) | No tags | |||||
| Hotelu Grand | Brussels Airport BRU (Parking P14) | No tags | |||||
| Hotelu Grand | Brussels North Train Station | No tags |
Last refresh of the prices: Yesterday at 11:36 AM CEST.
Compare 2 ways to go from Brno to Brussels
Among the sustainable travel choices, the Bus stands out as a good way to reach Brussels. The journey takes about 21 hours 20 minutes, and with fares starting at just PEN 228, it presents an excellent value for a comfortable ride.
Bus stations and stops in Brno and Brussels
Stops in Brno
- A
Hotelu Grand
Benešova 603/2, Brno-město, 602 00 Brno-Brno-střed, Czech Republic - B
Hlavní nádraží
Nádražní 418/1, Brno-město, 602 00 Brno-Brno-střed, Czechia - C
Brno Bus Station
Brno Bus Station, ÚAN Zvonařka, 602 00 Brno-střed, Czechia - D
ÚAN Zvonařka
Zvonařka 411, Trnitá, 602 00 Brno-Brno-střed, Czech Republic - E
Židenice
Lazaretní 610/11, 615 00 Brno-Brno-Židenice, Czechia - F
Vídeňská 98
Vídeňská 98, 619 00 Brno-jih, Czechia
Stops in Brussels
- A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium - B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium - C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium - D
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
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Frequently asked questions about travelling from Brno to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Brno to Brussels?
The cheapest bus tickets from Brno to Brussels start from PEN 228. The average price for this route is around PEN 423. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brno to Brussels?
The average bus travel time from Brno to Brussels is 21h 20m, covering a distance of 893 km. The quickest bus can get you there in 16h and is operated by RegioJet.
Which bus companies service the Brno to Brussels route?
What are the earliest and latest departure times for the bus from Brno to Brussels?
The earliest bus departs from Brno to Brussels at 1:30am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Brno to Brussels?
A bus trip from Brno to Brussels generates an estimated 22.3141 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Brno to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1106 reviews.
Which bus company has the best Wi-Fi from Brno to Brussels?
Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.7.
Which bus company has the best on-time performance from Brno to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Brno to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brno to Brussels was searched and found on Sep 9, 2026 with a price of PEN 180To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brno to Brussels, as early as possible.
You can expect to pay from PEN 180 to PEN 532 for a bus ticket from Brno to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at PEN 213 which is on 2026-09-11.
What's the cheapest way to go from Brno to Brussels?
The Bus is the cheapest travel choice for this destination
