Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Brussels North Train Station | Mainz | CheapestFastest | ||||
| Bus | Brussels South (Gare du Midi) | Mainz | No tags |
Last refresh of the prices: Yesterday at 12:55 PM CET.
Compare 3 ways to go from Brussels to Mainz
Among the sustainable travel choices, the carpool stands out as a good way to reach Mainz. The journey takes about 3 hours 40 minutes, and with fares starting at just $48, it presents an excellent value for a comfortable ride.
Where are the popular stops in Brussels and Mainz?
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Stops in Mainz
- A
Mainz
Hechtsheimer Str. 65, 55131 Mainz, Germany - B
Mainz- Kaiser-Wilhelm-Ring 16- gegenüberliegende Straßenseite
Kaiser-Wilhelm-Ring 16 (gegenüberliegende Straßenseite), 55118 Mainz - Cflibco.com bus stop, Kaiser-Wilhelm-Ring, 55118 Mainz, Germany
Compare bus companies
Based on 11507 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $40
Frequently asked questions about travelling from Brussels to Mainz by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Brussels to Mainz?
The cheapest bus tickets from Brussels to Mainz start from $40. The average price for this route is around $65. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brussels to Mainz?
The average bus travel time from Brussels to Mainz is 10h 50m, covering a distance of 293 km. The quickest bus can get you there in 5h 25m and is operated by FlixBus.
Which bus companies service the Brussels to Mainz route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Brussels to Mainz?
The earliest bus departs from Brussels to Mainz at 2:10am. And the latest bus departs at 9:45pm.
What are the CO₂ emissions for the bus trip from Brussels to Mainz?
A bus trip from Brussels to Mainz generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Mainz was searched and found on Dec 3, 2025 with a price of $40To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Mainz, as early as possible.
