Bus from Des Moines to Buffalo, NY: Tickets & Schedules

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Next departures for Des Moines to Buffalo on January 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound + FlixBus	Bus	5:30am	Des Moines (Subway)	2d 1h	7:55am	Buffalo (BUF) Airport	No tags
FlixBus + Greyhound	Bus	5:30am	Des Moines (Subway)	2d 1h	7:55am	Buffalo (BUF) Airport	No tags
FlixBus + Greyhound	Bus	5:30am	Des Moines (Subway)	2d 1h	7:55am	Buffalo (BUF) Airport	No tags

Get from Des Moines to Buffalo

This route is served by bus only

The journey takes about 2 days, 1 hour 25 minutes, and with fares starting at just $383, it presents an excellent value for a comfortable ride.

1bus per day

2d 1hAverage Duration

1231 kmDistance

31kgCO₂ emissions

Where are the popular stops in Des Moines and Buffalo?

Stops in Des Moines

A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314
Map
B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Map

Stops in Buffalo

A
Buffalo Airport
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B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA
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C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
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