Bus from Des Moines to Buffalo, NY: Tickets & Schedules

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Previously seen trips

Next departures for Des Moines to Buffalo on January 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound + FlixBus	Bus	5:30am	Des Moines (Subway)	2d 1h	7:55am	Buffalo (BUF) Airport	No tags
FlixBus + Greyhound	Bus	5:30am	Des Moines (Subway)	2d 1h	7:55am	Buffalo (BUF) Airport	No tags
FlixBus + Greyhound	Bus	5:30am	Des Moines (Subway)	2d 1h	7:55am	Buffalo (BUF) Airport	No tags

Get from Des Moines to Buffalo

This route is served by bus only

The journey takes about 2 days, 1 hour 25 minutes and with fares starting at just $269, it presents an excellent value for a comfortable ride.

1bus per day

2d 1hAverage Duration

764 milesDistance

31kgCO₂ emissions

Where are the popular stops in Des Moines and Buffalo?

Stops in Des Moines

A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314
Map
B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Map

Stops in Buffalo

A
Buffalo Airport
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B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA
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C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
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