Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Alte Eppelheimer Straße | Prague (Central Bus Station Florenc) | Cheapest | ||||
| Bus | Alte Eppelheimer Straße | Prague (Na Knížecí) | Fastest | ||||
| Bus | Alte Eppelheimer Straße | PRG Airport | No tags | ||||
| Bus | Alte Eppelheimer Straße | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Alte Eppelheimer Straße | Prague (Central Bus Station Florenc) | No tags |
Last refresh of the prices: Yesterday at 4:02 PM CEST.
Compare 2 ways to go from Heidelberg to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 7 hours 15 minutes, and with fares starting at just $37, it presents an excellent value for a comfortable ride.
Where are the popular stops in Heidelberg and Prague?
Stops in Heidelberg
- A
Südseite am Willi-Brandt-Platz
Willy-Brandt-Platz 1, 69115 Heidelberg, Germany - B
Heidelberg
Willy-Brandt-Platz 5, 69115 Heidelberg, Germany - C
Heidelberg Central Station
Kurfürsten-Anlage 60, 69115 Heidelberg, Germany
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- CChlumecká, 198 00 Praha 20, Czech Republic
- DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F300/8 Wilsonova, 110 00 Praha, Czechia
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Frequently asked questions about travelling from Heidelberg to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Heidelberg to Prague?
The cheapest bus tickets from Heidelberg to Prague start from $37. The average price for this route is around $67. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Heidelberg to Prague?
The average bus travel time from Heidelberg to Prague is 7h 15m, covering a distance of 422 km. The quickest bus can get you there in 6h 40m and is operated by FlixBus.
Which bus companies service the Heidelberg to Prague route?
Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus, Lux Reisen, BlaBlaCar Bus.
What are the earliest and latest departure times for the bus from Heidelberg to Prague?
The earliest bus departs from Heidelberg to Prague at 2:55am. And the latest bus departs at 10:40pm.
What are the CO₂ emissions for the bus trip from Heidelberg to Prague?
A bus trip from Heidelberg to Prague generates an estimated 10.529325 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Heidelberg to Prague?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11593 reviews.
Which bus company has the best Wi-Fi from Heidelberg to Prague?
Based on Busbud reviews, the bus company Lux Reisen has the highest Wi-Fi rating with a score of 3.4.
Which bus company has the best on-time performance from Heidelberg to Prague?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Heidelberg to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Lux Reisen, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Heidelberg to Prague was searched and found on Apr 14, 2026 with a price of $34To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Heidelberg to Prague, as early as possible.
You can expect to pay from $34 to $67 for a bus ticket from Heidelberg to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $38 which is on 2026-04-18.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Heidelberg to Prague?
The Bus is the cheapest travel choice for this destination
