Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Flixtrain + Flixbus | Heidelberg Hauptbahnhof | Prague (Main Station - parking) | Cheapest | |||||
 | Alte Eppelheimer Straße | Prague (Na Knížecí) | Fastest | |||||
| Alte Eppelheimer Straße | PRG Airport | No tags | |||||
| Alte Eppelheimer Straße | Prague (Central Bus Station Florenc) | No tags | |||||
| Alte Eppelheimer Straße | Prague (Central Bus Station Florenc) | No tags | |||||
| Alte Eppelheimer Straße | Prague (Central Bus Station Florenc) | No tags | |||||
| Alte Eppelheimer Straße | Prague (Central Bus Station Florenc) | No tags | |||||
| Alte Eppelheimer Straße | Prague (Main Railway Station) | No tags |
Last refresh of the prices: Yesterday at 2:26 PM CEST.
Compare 2 ways to go from Heidelberg to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 8 hours 40 minutes and with fares starting at just CHF 22, it presents an excellent value for a comfortable ride.
Bus stations and stops in Heidelberg and Prague
Stops in Heidelberg
- A
Südseite am Willi-Brandt-Platz
Willy-Brandt-Platz 1, 69115 Heidelberg, Germany - B
Heidelberg
Willy-Brandt-Platz 5, 69115 Heidelberg, Germany - C
Heidelberg Central Station
Kurfürsten-Anlage 60, 69115 Heidelberg, Germany
Stops in Prague
- A
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - B
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - C
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic - D
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia - E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
Frequently asked questions about traveling from Heidelberg to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Heidelberg to Prague?
The cheapest bus tickets from Heidelberg to Prague start from CHF 22. The average price for this route is around CHF 48. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Heidelberg to Prague?
The average bus trip duration from Heidelberg to Prague is 8h 40m, covering a distance of 260 miles (419 km). The quickest bus can get you there in 6h 40m and is operated by FlixBus.
Which bus companies service the Heidelberg to Prague route?
Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus, BlaBlaCar Bus, KLR Bus, Lux Reisen.
What is the earliest and latest departure time for the bus from Heidelberg to Prague?
The earliest bus departs from Heidelberg to Prague at 2:55am. And the latest bus departs at 10:40pm.
What are the CO₂ emissions for the bus trip from Heidelberg to Prague?
A bus trip from Heidelberg to Prague generates an estimated 10.470274999999999 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Heidelberg to Prague?
According to Busbud customers, the highest-rated bus company on this route is KLR Bus, with an average rating of 4.0 out of 5 stars based on 23 reviews.
Which bus company has the best Wi-Fi from Heidelberg to Prague?
Based on reviews on Busbud, the bus company KLR Bus has the best Wi-Fi rating with a score of 4.3.
Which bus company has the most timely service from Heidelberg to Prague?
According to Busbud traveler reviews, the most timely bus company on this route is KLR Bus, with a punctuality rating of 4.4 out of 5 stars.
Which bus company has the cleanest buses from Heidelberg to Prague?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Lux Reisen, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Heidelberg to Prague was searched and found on Sep 8, 2026 with a price of CHF 20To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Heidelberg to Prague, as early as possible.
You can expect to pay from CHF 20 to CHF 91 for a bus ticket from Heidelberg to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at CHF 20 which is on 2026-09-08.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
