Bus Tickets from Karlsruhe to Prague

Find affordable bus tickets from Karlsruhe to Prague with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 7
TomorrowMay 8
from US$30
FriMay 9
from US$38
SatMay 10
from US$38
SunMay 11
from US$39
MonMay 12
TueMay 13
WedMay 14

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: May 8 at
    Departure city: Karlsruhe
    Departure location: Südseite Hauptbahnhof
    Arrival time: May 9 at
    Destination city: Prague
    Destination location: PRG Airport
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Karlsruhe
    Departure location: Karlsruhe
    Arrival time: May 8 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Karlsruhe
    Departure location: Südseite Hauptbahnhof
    Arrival time: May 8 at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Karlsruhe
    Departure location: Südseite Hauptbahnhof
    Arrival time: May 8 at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Karlsruhe
    Departure location: Südseite Hauptbahnhof
    Arrival time: May 8 at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Last refresh of the prices: Last Monday at 8:11 PM CEST.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 3 ways to go from Karlsruhe to Prague

Bus
Average PriceUS$30 - US$140Average Duration10h 25m
11kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average PriceUS$45 - US$226Average Duration10h 16m
11kg CO₂e5 out of 5 stars
Carpool
Average PriceUS$29 - US$60Average Duration5h
19kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Karlsruhe to Prague

Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours, and with fares starting at just US$29, it presents an excellent value for a comfortable ride.

3carpool per day
5hAverage Duration
US$29Cheapest ticket
19kgCO₂ emissions

Bus Karlsruhe to Prague: Trip Overview

Average Ticket PriceUS$55
Average Bus Trip Duration10h 25m
Number of daily buses9
Earliest bus departure12:05am
Distance441 km
Latest bus departure11:30pm

Karlsruhe to Prague Bus

Busbud helps you find a bus from Karlsruhe to Prague. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Karlsruhe to Prague will be provided by the most trusted bus companies.

Discover how much the bus trip from Karlsruhe to Prague will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Karlsruhe - Prague

  1. How long is the trip from Karlsruhe to Prague by bus?

    The bus ride from Karlsruhe to Prague takes 10h 25m, on average. For the shortest travel time, select the fastest bus available, which will take you to Prague in about 7h 45m.

  2. What is the travel distance from Karlsruhe to Prague?

    The distance between Karlsruhe and Prague is approximately 453 km (281 miles).

  3. What are the departure and arrival locations for buses traveling from Karlsruhe to Prague?

    Buses departing from Südseite Hauptbahnhof in Karlsruhe will take you to Florenc in Prague.

  4. What is the cheapest way to get from Karlsruhe to Prague?

    The least expensive option to go from Karlsruhe to Prague would be going by bus. Starting at US$30, this bus is the most cost-effective option for your journey.

  5. How much does the bus ticket cost from Karlsruhe to Prague?

    You can expect to pay around US$55 for the bus ride from Karlsruhe to Prague.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-05
US$38
05-06
No data
Today
No data
05-08
US$27
05-09
US$35
05-10
US$35
05-11
US$36
05-12
US$34
busbud logoThe cheapest trip from Karlsruhe to Prague was searched and found on May 8, 2025 with a price of US$27

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Prague, as early as possible.

You can expect to pay from US$27 to US$46 for a bus ticket from Karlsruhe to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at US$27 which is on 2025-05-08.

Usually Comuto Pro (BlaBlaCar Bus) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Karlsruhe and Prague!

Much more than a mere vehicle taking you from Karlsruhe to Prague, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Karlsruhe to Prague will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Karlsruhe to Prague while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Karlsruhe by bus?

Bus from Karlsruhe to Prague

You can also go to Prague by train

Train from Karlsruhe to Prague

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Karlsruhe

Buses Leaving from Karlsruhe

Buses Going to Karlsruhe

Popular Buses Connecting Prague

Buses Leaving from Prague

Buses Going to Prague