Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Südseite Hauptbahnhof | Rome Anagnina | No tags | ||||
| Bus | Südseite Hauptbahnhof | Aeroporto Ciampino Airport (CIA) | No tags | ||||
| Bus | Südseite Hauptbahnhof | Rome Fiumicino Airport | No tags | ||||
| Bus | Südseite Hauptbahnhof | Rome Anagnina | No tags | ||||
| Bus | Südseite Hauptbahnhof | Rome Tiburtina Bus Station | No tags |
Compare 2 ways to go from Karlsruhe to Rome
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as a good way to reach Rome. The journey takes about 11 hours 30 minutes, and with fares starting at just $120, it presents an excellent value for a comfortable ride.
1carpool per day
11h 30mAverage Duration
853 kmDistance
36kgCO₂ emissions
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$77 - $208 | Average Duration19h 5m | 21kg CO₂e | ||
Carpool | Average Price$120 - $120 | Average Duration11h 30m | 36kg CO₂e |
Where are the popular stops in Karlsruhe and Rome?
Stops in Karlsruhe
- AHinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
- BBahnhofpl. 1A, 76137 Karlsruhe, Germany
- CGoethestraße 17-19, 76135 Karlsruhe, Germany
- D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany - E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
3.5 out of 5 stars3.5/511,454 reviews
3.5 out of 5 stars3.5/511,165 reviews
4 out of 5 stars4/5896 reviews
IT Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about travelling from Karlsruhe to Rome by bus
What is the travel distance from Karlsruhe to Rome?
The distance covered from Karlsruhe to Rome is 854 km (530 miles).
What are the departure and arrival locations for buses traveling from Karlsruhe to Rome?
Buses traveling this route start their trip at Südseite Hauptbahnhof, in Karlsruhe, and end it at Rome Tiburtina Bus Station, in Rome.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-25
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Today
$109
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The cheapest trip from Karlsruhe to Rome was searched and found on Nov 27, 2025 with a price of $109To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Rome, as early as possible.
What's the cheapest way to go from Karlsruhe to Rome?
The bus is the cheapest travel choice for this destination
