Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Arrêt D'autobus Lugano | Brussels-South (Gare du Midi) | No tags | ||||
 | Bus | Lugano | Brussels-North (Gare du Nord) | No tags | ||||
| Bus | Lugano | Brussels Airport | No tags | ||||
| Bus | Lugano | Brussels-North (Gare du Nord) | No tags | ||||
| Bus | Lugano | Brussels South (Gare du Midi) | No tags |
Compare 2 ways to go from Lugano to Brussels
Among the sustainable travel choices, the carpool stands out as a good way to reach Brussels. The journey takes about 9 hours 10 minutes, and with fares starting at just $115, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$78 - $301 | Average Duration20h | 16kg CO₂e | ||
Carpool | Average Price$115 - $115 | Average Duration9h 10m | 27kg CO₂e |
Where are the popular stops in Lugano and Brussels?
Stops in Lugano
- AVia Giacomo E Filippo Ciani, 6900 Lugano, Switzerland
- B
Stazione/Gare de Lugano
Stazione FFS 1, 6900 Lugano, Switzerland - C
Via Basilea
Via Basilea, 6900 Lugano, Switzerland
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Compare bus companies
Frequently asked questions about travelling from Lugano to Brussels by bus
What is the distance between Lugano and Brussels?
It's about 638 km (396 miles) from Lugano to Brussels.
What are the departure and arrival locations for buses traveling from Lugano to Brussels?
Buses traveling this route start their trip at Arrêt D'autobus Lugano, in Lugano, and end it at Brussels South (Gare du Midi), in Brussels.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lugano to Brussels was searched and found on Nov 21, 2025 with a price of $73To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lugano to Brussels, as early as possible.
You can expect to pay from $73 to $296 for a bus ticket from Lugano to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $78 which is on 2025-11-23.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
