Next departures for Lugano to Brussels on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lugano
Brussels North Train Station
Cheapest
Bus
Lugano
Brussels North Train Station
Fastest
Bus
Lugano
Brussels Airport
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Bus
Lugano
Brussels Airport
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Bus
Lugano
Brussels North Train Station
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Next departures for Lugano to Brussels on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lugano
Brussels North Train Station
Cheapest
Bus
Lugano
Brussels North Train Station
Fastest
Bus
Lugano
Brussels Airport
No tags
Bus
Lugano
Brussels Airport
No tags
Bus
Lugano
Brussels Airport
No tags
Last refresh of the prices: Last Friday at 11:52 AM CET.
Compare 2 ways to go from Lugano to Brussels
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Brussels. The journey takes about 9 hours 10 minutes and with fares starting at just $80, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11138 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $54
Frequently asked questions about traveling from Lugano to Brussels by bus
What is the distance between Lugano and Brussels?
The distance separating Lugano and Brussels is 396 miles (638 km).
What are the departure and arrival stations when taking the bus from Lugano to Brussels?
If you're headed to Brussels from Lugano, chances are that your bus will leave from Arrêt D'autobus Lugano and arrive at Brussels South (Gare du Midi). These are the main pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Brussels?
Once in Brussels, you can start exploring the city and discover its surroundings. The top sights and things to do are Pride Festival in Brussels, Le Tour - Brussels Grand Départ, Bright Brussels Festival, 20km of Brussels - 36 years of Brussels' most popular race and Visit the Laeken Royal Greenhouses in Brussels.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
No data
11/18
No data
Today
$56
11/20
$58
11/21
$50
11/22
No data
11/23
$54
11/24
No data
The cheapest trip from Lugano to Brussels was searched and found on Nov 21, 2025 with a price of $50
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lugano to Brussels, as early as possible.
You can expect to pay from $50 to $205 for a bus ticket from Lugano to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $50 which is on 2025-11-21.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Lugano to Brussels was searched and found on Nov 21, 2025 with a price of $50
