Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Lampugnano | Brussels-South (Gare du Midi) | CheapestFastest |
Last refresh of the prices: Yesterday at 6:26 PM CET.
Compare 2 ways to go from Milano to Brussels
Among the sustainable travel choices, the carpool stands out as a good way to reach Brussels. The journey takes about 10 hours 10 minutes, and with fares starting at just $68, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$69 - $347 | Average Duration20h 10m | 17kg CO₂e | ||
Carpool | Average Price$68 - $127 | Average Duration10h 10m | 29kg CO₂e |
Where are the popular stops in Milano and Brussels?
Stops in Milano
- APiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- CVia Giulio Natta, 228, 20151 Milano, Italy
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Compare bus companies
Frequently asked questions about travelling from Milano to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Milano to Brussels?
The cheapest bus tickets from Milano to Brussels start from $69. The average price for this route is around $132. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milano to Brussels?
The average bus travel time from Milano to Brussels is 20h 10m, covering a distance of 663 km. The quickest bus can get you there in 12h 45m and is operated by BlaBlaCar Bus.
Which bus companies service the Milano to Brussels route?
Several major bus companies operate on this route with 20 buses available per day, including services from FlixBus, BlaBlaCar Bus, OneBus.
What are the earliest and latest departure times for the bus from Milano to Brussels?
The earliest bus departs from Milano to Brussels at 12:30am. And the latest bus departs at 11:55pm.
What are the CO₂ emissions for the bus trip from Milano to Brussels?
A bus trip from Milano to Brussels generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Milano to Brussels?
According to Busbud customers, the highest-rated bus company on this route is OneBus, with an average rating of 4.2 out of 5 stars based on 13 reviews.
Which bus company has the best Wi-Fi from Milano to Brussels?
Based on Busbud reviews, the bus company OneBus has the highest Wi-Fi rating with a score of 5.0.
Which bus company has the best on-time performance from Milano to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is OneBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Milano to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is OneBus, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milano to Brussels was searched and found on Dec 2, 2025 with a price of $75To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Brussels, as early as possible.
You can expect to pay from $75 to $274 for a bus ticket from Milano to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $75 which is on 2025-12-02.
