Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Syracuse bus station | Terminal Bus Palermo | Cheapest | ||||
| Bus | Syracuse bus station | Palermo Oreto Orsi | Fastest | ||||
| Bus | Syracuse bus station | Terminal Bus Palermo | No tags | ||||
 | Bus | Terminal Interbus | Terminal Bus Palermo | No tags | ||||
| Bus | Syracuse bus station | Terminal Bus Palermo | No tags |
Last refresh of the prices: Yesterday at 8:47 AM CET.
Compare 3 ways to go from Syracuse to Palermo
Among the sustainable travel choices, the Carpool stands out as a good way to reach Palermo. The journey takes about 3 hours 10 minutes, and with fares starting at just $21, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Palermo?
Stops in Syracuse
- AViale Paolo Orsi, 20, 96100 Siracusa SR, Italy
- B
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - C
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
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Frequently asked questions about travelling from Syracuse to Palermo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Palermo?
The cheapest bus tickets from Syracuse to Palermo start from $27. The average price for this route is around $29. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Palermo?
The average bus travel time from Syracuse to Palermo is 3h 15m, covering a distance of 205 km. The quickest bus can get you there in 3h 10m and is operated by Interbus Italy.
Which bus companies service the Syracuse to Palermo route?
Several major bus companies operate on this route with 5 buses available per day, including services from Interbus Italy, FlixBus.
What are the earliest and latest departure times for the bus from Syracuse to Palermo?
The earliest bus departs from Syracuse to Palermo at 7:15am. And the latest bus departs at 5:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Palermo?
A bus trip from Syracuse to Palermo generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Syracuse to Palermo?
According to Busbud customers, the highest-rated bus company on this route is Interbus Italy, with an average rating of 4.0 out of 5 stars based on 604 reviews.
Which bus company has the best Wi-Fi from Syracuse to Palermo?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Syracuse to Palermo?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Palermo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Interbus Italy, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse to Palermo was searched and found on Feb 22, 2026 with a price of $26To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to Palermo, as early as possible.
You can expect to pay from $26 to $35 for a bus ticket from Syracuse to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $26 which is on 2026-02-25.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Syracuse to Palermo?
The Bus is the cheapest travel choice for this destination
