Bus Tickets from Boston, MA to Florence, SC

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TodayMay 15
TomorrowMay 16
from US$126
SatMay 17
from US$113
SunMay 18
MonMay 19
TueMay 20
WedMay 21
from US$138
ThuMay 22

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 16 at
    Departure city: Boston
    Departure location: 151 Steel Pl, Cambridge
    Arrival time: May 17 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 16 at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: May 17 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 16 at
    Departure city: Boston
    Departure location: Boston (South Station)
    Arrival time: May 17 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 16 at
    Departure city: Boston
    Departure location: Boston
    Arrival time: May 17 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: May 16 at
    Departure city: Boston
    Departure location: Boston
    Arrival time: May 18 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Friday at 2:33 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
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  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Boston to Florence

Bus
Average PriceUS$87 - US$198Average Duration1d 8h
30kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$196 - US$471Average Duration17h 30m
107kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Boston to Florence

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 17 hours 30 minutes, and with fares starting at just US$196, it presents an excellent value for a comfortable ride.

6train per day
17h 30mAverage Duration
US$196Cheapest ticket
107kgCO₂ emissions

Bus Boston to Florence: Trip Overview

Average Ticket PriceUS$126
Average Bus Trip Duration1d 8h
Number of daily buses3
Earliest bus departure1:30am
Distance1182 km
Latest bus departure8:55pm

Boston to Florence Bus

With Busbud, comparing and booking tickets for a bus from Boston to Florence is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Boston to Florence.

Whether it is cheap bus tickets or more luxurious buses going to Florence from Boston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Boston - Florence

  1. How long is the trip from Boston to Florence by bus?

    The trip from Boston to Florence will take on average 1d 8h. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 18h 20m.

  2. What is the travel distance from Boston to Florence?

    It's about 1176 km (729 miles) from Boston to Florence.

  3. What are the departure and arrival locations for buses traveling from Boston to Florence?

    Buses traveling this route start their trip at South Station, in Boston, and end it at Florence Bus Station, in Florence.

  4. What is the cheapest way to travel from Boston to Florence?

    If you're on a budget, consider traveling by bus to Florence from Boston; it tends to be more affordable. Starting at US$87, this bus is the most cost-effective option for your journey.

  5. How much does the bus ticket cost from Boston to Florence?

    Taking the bus from Boston to Florence costs on average US$126.

  6. Is there an overnight bus from Boston to Florence?

    Yes! Catch buses leaving from Boston until 8:55pm and reaching Florence on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-13
No data
05-14
No data
Today
No data
05-16
US$149
05-17
US$128
05-18
No data
05-19
No data
05-20
No data
busbud logoThe cheapest trip from Boston to Florence was searched and found on May 17, 2025 with a price of US$128

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston to Florence, as early as possible.

You can expect to pay from US$128 to US$149 for a bus ticket from Boston to Florence based on the last 2 days. You can expect to find the cheapest price for the trip at US$128 which is on 2025-05-17.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Boston to Florence.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Boston to Florence.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Boston to Florence.

Make a music playlist for your bus ride from Boston to Florence, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Boston to Florence?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Boston by bus?

Bus from Boston to Florence

You can also go to Florence by train

Train from Boston to Florence

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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