Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Boston (South Station) | Florence, SC | Cheapest | ||||
 | Bus | Boston (South Station) | Bus station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | Florence, SC | No tags |
Last refresh of the prices: Yesterday at 1:37 AM EST.
Compare 2 ways to go from Boston to Florence
Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 1 day, 4 hours 15 minutes, and with fares starting at just $137, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and Florence?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C335 Grove St, Auburndale, MA 02466
- D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about travelling from Boston, MA, US to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Boston to Florence?
The cheapest bus tickets from Boston to Florence start from $137. The average price for this route is around $271. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Boston to Florence?
The average bus travel time from Boston to Florence is 1d 4h, covering a distance of 1178 km. The quickest bus can get you there in 19h and is operated by Greyhound.
Which bus companies service the Boston to Florence route?
What are the earliest and latest departure times for the bus from Boston to Florence?
The earliest bus departs from Boston to Florence at 1:30am. And the latest bus departs at 9:50pm.
What are the CO₂ emissions for the bus trip from Boston to Florence?
A bus trip from Boston to Florence generates an estimated 29 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Boston to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11799 reviews.
Which bus company has the best Wi-Fi from Boston to Florence?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Boston to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Boston to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Florence, SC, US was searched and found on Jan 9, 2026 with a price of $178To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Florence, SC, US, as early as possible.
What's the cheapest way to go from Boston, MA, US to Florence, SC, US?
The Bus is the cheapest travel choice for this destination
