Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Chicago (Union Station), IL | Florence Station | No tags | ||||
| Train | Chicago (Union Station), IL | Florence Station | No tags | ||||
| Train | Chicago (Union Station), IL | Florence Station | No tags | ||||
| Train | Chicago (Union Station), IL | Florence Station | No tags | ||||
| Train | Chicago (Union Station), IL | Florence Station | No tags |
Compare 2 ways to go from Chicago to Florence
Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 1 day, 4 hours 25 minutes, and with fares starting at just $156, it presents an excellent value for a comfortable ride.
Train companies
Based on 5644 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $280
Frequently asked questions about travelling from Chicago to Florence, SC, US by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Chicago to Florence?
The cheapest train tickets from Chicago to Florence start at $280. The average price for this train route is around $540. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Chicago to Florence?
The average train trip from Chicago to Florence takes 1d 7h and covers 1098 km. The quickest train gets you there in 1d 7h and is operated by Amtrak.
Which train operators serve the Chicago to Florence route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Chicago to Florence?
The earliest train from Chicago to Florence departs at 6:40pm. The latest train departs at 6:40pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Florence, SC, US was searched and found on Dec 15, 2025 with a price of $269To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Chicago to Florence, SC, US, as early as possible.
You can expect to pay from $269 to $1,419 for a train ticket from Chicago to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $269 which is on 2025-12-15.
