Previously seen trips

Next departures for Florence to Harrisburg on October 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
	Bus Wi‑Fi Toilet Power outlets	4:15pm	Bus station	22h 20m	2:35pm	Harrisburg
Greyhound + FlixBus	Bus Wi‑Fi Toilet Power outlets	12:05am	Florence, SC	13h 50m	1:55pm	Harrisburg Bus Station
FlixBus + Greyhound	Bus Wi‑Fi Toilet Power outlets	4:15pm	Bus station	20h 55m	1:10pm	Harrisburg Bus Station
Greyhound + FlixBus	Bus Wi‑Fi Toilet Power outlets	4:15pm	Bus station	20h 55m	1:10pm	Harrisburg Bus Station
FlixBus + Greyhound	Bus Wi‑Fi Toilet Power outlets	4:15pm	Bus station	20h 55m	1:10pm	Harrisburg Bus Station

Compare 2 ways to go from Florence to Harrisburg

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Harrisburg. The journey takes about 18 hours 10 minutes, and with fares starting at just $146, it presents an excellent value for a comfortable ride.

3bus per day

18h 10mAverage Duration

722 kmDistance

18kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$146 - $273	Average Duration18h 10m	CO₂ emissions 18kg CO₂e
Train	Average Price$273 - $448	Average Duration14h 15m	CO₂ emissions 66kg CO₂e

Bus stations and stops in Florence and Harrisburg

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Harrisburg

A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101

Compare bus companies

Greyhound

3.5/588,238 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wi‑Fi2.5

FlixBus

3.5/516,275 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

US bus companies:FlixBus, Greyhound, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit, Wanda Coach

Frequently asked questions about travelling from Florence, SC, US to Harrisburg by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Florence to Harrisburg?
The cheapest bus tickets from Florence to Harrisburg start from $146. The average price for this route is around $223. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Harrisburg?
The average bus travel time from Florence to Harrisburg is 18h 10m, covering a distance of 722 km. The quickest bus can get you there in 19h 50m and is operated by Greyhound.
Which bus companies service the Florence to Harrisburg route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Florence to Harrisburg?
The earliest bus departs from Florence to Harrisburg at 12:05am. And the latest bus departs at 7:20pm.
What are the CO₂ emissions for the bus trip from Florence to Harrisburg?
A bus trip from Florence to Harrisburg generates an estimated 18.045975000000002 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Florence to Harrisburg?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88213 reviews.
Which bus company has the best Wi-Fi from Florence to Harrisburg?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Florence to Harrisburg?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Harrisburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.