Next available departures

Next departures for Pisa to Milano on September 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	6:10pm	Parcheggio Via Pietransantina	6h 55m	1:05am	Lampugnano bus station	Cheapest
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	5h	4:30am	Milan (Assago M2)	Fastest
Wi‑Fi Toilet Power outlets	8:55am	Piazza della Stazione, 10	5h 5m	2:00pm	Milano Centrale	No tags
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	5h 50m	5:20am	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	6h	5:30am	Aeroporto Malpensa T2	No tags
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	7h	6:30am	Piazza I Maggio, 1	No tags
Wi‑Fi Toilet Power outlets	7:15am	Parcheggio Via Pietransantina	6h 10m	1:25pm	Lampugnano bus station	No tags
Wi‑Fi Toilet Power outlets	5:10pm	Parcheggio Via Pietransantina	6h 25m	11:35pm	Lampugnano bus station	No tags

Next departures for Pisa to Milano on September 24
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	5:10pm	Parcheggio Via Pietransantina	5h 50m	11:00pm	Milan (San Donato M3)	Cheapest
Wi‑Fi Toilet Power outlets	1:50pm	Parcheggio Via Pietransantina	4h 35m	6:25pm	Milan (Assago M2)	Fastest
Wi‑Fi Toilet Power outlets	8:55am	Piazza della Stazione, 10	5h 5m	2:00pm	Milano Centrale	No tags
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	5h 50m	5:20am	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	6h	5:30am	Aeroporto Malpensa T2	No tags
Wi‑Fi Toilet Power outlets	12:00pm	Parcheggio Via Pietransantina	8h 20m	8:20pm	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	12:00pm	Parcheggio Via Pietransantina	8h 10m	8:10pm	Aeroporto Malpensa T2	No tags
Wi‑Fi Toilet Power outlets	6:25am	Parcheggio Via Pietransantina	5h 30m	11:55am	Aeroporto Linate Airport (LIN)	No tags

Next departures for Pisa to Milano on September 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	5:10pm	Parcheggio Via Pietransantina	5h 50m	11:00pm	Milan (San Donato M3)	Cheapest
Wi‑Fi Toilet Power outlets	1:50pm	Parcheggio Via Pietransantina	4h 35m	6:25pm	Milan (Assago M2)	Fastest
Wi‑Fi Toilet Power outlets	8:55am	Piazza della Stazione, 10	5h 5m	2:00pm	Milano Centrale	No tags
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	5h 50m	5:20am	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	6h	5:30am	Aeroporto Malpensa T2	No tags
Wi‑Fi Toilet Power outlets	4:45am	Parcheggio Via Pietransantina	7h 30m	12:15pm	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	12:00pm	Parcheggio Via Pietransantina	8h 20m	8:20pm	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	4:45am	Parcheggio Via Pietransantina	7h 20m	12:05pm	Aeroporto Malpensa T2	No tags

Next departures for Pisa to Milano on September 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	7:15am	Parcheggio Via Pietransantina	6h 10m	1:25pm	Lampugnano bus station	Cheapest
Wi‑Fi Toilet Power outlets	1:50pm	Parcheggio Via Pietransantina	4h 35m	6:25pm	Milan (Assago M2)	Fastest
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	5h 50m	5:20am	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	6h	5:30am	Aeroporto Malpensa T2	No tags
Wi‑Fi Toilet Power outlets	4:45am	Parcheggio Via Pietransantina	7h 30m	12:15pm	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	12:00pm	Parcheggio Via Pietransantina	8h 20m	8:20pm	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	4:45am	Parcheggio Via Pietransantina	7h 20m	12:05pm	Aeroporto Malpensa T2	No tags
Wi‑Fi Toilet Power outlets	12:00pm	Parcheggio Via Pietransantina	8h 10m	8:10pm	Aeroporto Malpensa T2	No tags

Next departures for Pisa to Milano on September 27
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	7:15am	Parcheggio Via Pietransantina	6h 10m	1:25pm	Lampugnano bus station	Cheapest
Wi‑Fi Toilet Power outlets	4:56pm	Piazza della Stazione, 10	3h 44m	8:40pm	Milano Centrale	Fastest
Wi‑Fi Toilet Power outlets	4:56pm	Piazza della Stazione, 10	3h 44m	8:40pm	Milano Centrale	No tags
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	5h 50m	5:20am	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	11:30pm	park Aurelia	6h	5:30am	Aeroporto Malpensa T2	No tags
Wi‑Fi Toilet Power outlets	4:45am	Parcheggio Via Pietransantina	7h 30m	12:15pm	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	12:00pm	Parcheggio Via Pietransantina	8h 20m	8:20pm	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	4:45am	Parcheggio Via Pietransantina	7h 20m	12:05pm	Aeroporto Malpensa T2	No tags

Next departures for Pisa to Milano on September 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Wi‑Fi Toilet Power outlets	7:15am	Parcheggio Via Pietransantina	5h 30m	12:45pm	Milan (San Donato M3)	Cheapest
Wi‑Fi Toilet Power outlets	1:50pm	Parcheggio Via Pietransantina	4h 35m	6:25pm	Milan (Assago M2)	Fastest
Wi‑Fi Toilet Power outlets	8:55am	Piazza della Stazione, 10	5h 5m	2:00pm	Milano Centrale	No tags
Wi‑Fi Toilet Power outlets	4:45am	Parcheggio Via Pietransantina	7h 30m	12:15pm	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	12:00pm	Parcheggio Via Pietransantina	8h 20m	8:20pm	Milan (Malpensa Airport Terminal 1)	No tags
Wi‑Fi Toilet Power outlets	4:45am	Parcheggio Via Pietransantina	7h 20m	12:05pm	Aeroporto Malpensa T2	No tags
Wi‑Fi Toilet Power outlets	12:00pm	Parcheggio Via Pietransantina	8h 10m	8:10pm	Aeroporto Malpensa T2	No tags
Wi‑Fi Toilet Power outlets	6:25am	Parcheggio Via Pietransantina	5h 30m	11:55am	Aeroporto Linate Airport (LIN)	No tags

Last refresh of the prices: Today at 3:57 PM CEST.

Compare 2 ways to go from Pisa to Milano

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Milano. The journey takes about 6 hours, and with fares starting at just MAD 159, it presents an excellent value for a comfortable ride.

16bus per day

6hAverage Duration

226 kmDistance

6kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceMAD 159 - MAD 1,273	Average Duration6h	CO₂ emissions 6kg CO₂e
Train	Average PriceMAD 229 - MAD 870	Average Duration5h 5m	CO₂ emissions 5kg CO₂e

Bus stations and stops in Pisa and Milano

Stops in Pisa

A
Piazza della Stazione, 10
Piazza della Stazione, 10, 56125 Pisa PI, Italy
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B
Pisa Airport
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C
Parcheggio Via Pietransantina
Via Pietrasantina, 56123 Pisa PI
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D
Stazione Ferroviaria Pisa Centrale - Fermata dell'autobus
Via Giuseppe Sainati 16, 56121 Pisa PI, Italy
E
Tombolo
Via Aurelia, 325, 56121 Pisa PI, Italy
F
San Rossore
56122 Pisa PI, Italy

Stops in Milano

A
Milano Centrale
Piazza Duca d'Aosta 1, 20124 Milano MI, Italy
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B
Rogoredo
Via Gamboloita 7, 20139 Milano MI, Italy
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C
Rho Fiera
20017 Rho MI, Italy
Visit page
D
Piazza I Maggio, 1
Piazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
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E
Porta Garibaldi
P.za Sigmund Freud 1, 20124 Milano MI, Italy
Visit page
F
Lampugnano
Via Giulio Natta, 228, 20151 Milano, Italy
Visit page

Compare companies

FlixBus

3.5/515,833 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wi‑Fi2.7

Trenitalia

3.9/571 reviews

Staff4.5

Timeliness4.5

Cleanliness4.8

Wi‑Fi2.9

Itabus

3.8/51,078 reviews

Staff4.3

Timeliness3.1

Cleanliness4.1

Wi‑Fi2.9

Companies in IT:FlixBus, Trenitalia, BlaBlaCar Bus, Deutsche Bahn, ALSA, FlixTrain, Rede Expressos, RegioJet, Trenitalia, NS Nederlandse Spoorwegen, Deutsche Bahn, Deutsche Bahn Regio, Sindbad, Italo

Frequently asked questions about travelling from Pisa to Milano by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is a ticket from Pisa to Milano?
The cheapest tickets from Pisa to Milano start at MAD 159. The average price for this route is around MAD 433. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the ride from Pisa to Milano?
The average trip duration from Pisa to Milano is 5h 32m, covering a distance of 223 km. The quickest vehicle can get you there in 3h 44m and is operated by Trenitalia.
Which companies service the Pisa to Milano route?
Several major companies operate on this route with 8 trips available per day, including services from FlixBus, Itabus, Trenitalia.
What is the earliest and latest departure time from Pisa to Milano?
The earliest trip from Pisa to Milano departs at 4:45am. And the latest trip departs at 11:30pm.
What are the CO₂ emissions for the trip from Pisa to Milano?
A trip from Pisa to Milano generates an estimated 5.554212499999999 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best company from Pisa to Milano?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 3.9 out of 5 stars based on 71 reviews.
Which company has the best Wi-Fi from Pisa to Milano?
Based on Busbud reviews, the company Trenitalia has the highest Wi‑Fi rating with a score of 2.9.
Which company has the most on-time service from Pisa to Milano?
According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.5 out of 5 stars.
Which company has the cleanest vehicles from Pisa to Milano?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.8 out of 5 stars.

Find the cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09-20

MAD 432

09-21

MAD 265

Today

MAD 192

09-23

MAD 190

09-24

MAD 190

09-25

MAD 242

09-26

MAD 231

09-27

MAD 288

The cheapest trip from Pisa to Milano was searched and found on Sep 24, 2026 with a price of MAD 190

To save money and make sure you have the best seat, it's a good idea to buy your bus and train tickets from Pisa to Milano, as early as possible.

You can expect to pay between MAD 190 and MAD 765 for a bus or train ticket from Pisa to Milano based on the past 2 days. You can expect to find the lowest price for this trip at MAD 190 on 2026-09-24.