Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Parcheggio Via Pietransantina | Lampugnano bus station | Cheapest | |||||
| Parcheggio Via Pietransantina | Milan (Assago M2) | Fastest | |||||
 | Piazza della Stazione, 10 | Rogoredo | No tags | |||||
| park Aurelia | Milan (Malpensa Airport Terminal 1) | No tags | |||||
| Piazza della Stazione, 10 | Rogoredo | No tags |
Last refresh of the prices: Yesterday at 11:47 AM CEST.
Compare 2 ways to go from Pisa to Milano
Among the sustainable travel choices, the Train stands out as a good way to reach Milano. The journey takes about 5 hours 5 minutes, and with fares starting at just $35, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Milano?
Stops in Pisa
- A
Piazza della Stazione, 10
Piazza della Stazione, 10, 56125 Pisa PI, Italy - C
Parcheggio Via Pietransantina
Via Pietrasantina, 56123 Pisa PI - D
Stazione Ferroviaria Pisa Centrale - Fermata dell'autobus
Via Giuseppe Sainati 16, 56121 Pisa PI, Italy - E
Tombolo
Via Aurelia, 325, 56121 Pisa PI, Italy - F
San Rossore
56122 Pisa PI, Italy
Stops in Milano
- A
Milano Centrale
Piazza Duca d'Aosta 1, 20124 Milano MI, Italy - B
Rogoredo
Via Gamboloita 7, 20139 Milano MI, Italy - C
Rho Fiera
20017 Rho MI, Italy - D
Piazza I Maggio, 1
Piazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy - E
Lampugnano
Via Giulio Natta, 228, 20151 Milano, Italy - F
Porta Garibaldi
P.za Sigmund Freud 1, 20124 Milano MI, Italy
Compare companies
Frequently asked questions about travelling from Pisa to Milano by bus or train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is a ticket from Pisa to Milano?
The cheapest tickets from Pisa to Milano start at $32. The average price for this route is around $69. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the ride from Pisa to Milano?
The average trip duration from Pisa to Milano is 5h 32m, covering a distance of 223 km. The quickest vehicle can get you there in 3h 44m and is operated by Trenitalia.
Which companies service the Pisa to Milano route?
Several major companies operate on this route with 9 trips available per day, including services from FlixBus, Itabus, Trenitalia.
What is the earliest and latest departure time from Pisa to Milano?
The earliest trip from Pisa to Milano departs at 4:45am. And the latest trip departs at 11:30pm.
What are the CO₂ emissions for the trip from Pisa to Milano?
A trip from Pisa to Milano generates an estimated 5.5531500000000005 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best company from Pisa to Milano?
According to Busbud customers, the highest-rated company on this route is Trenitalia, with an average rating of 4.0 out of 5 stars based on 59 reviews.
Which company has the best Wi-Fi from Pisa to Milano?
Based on Busbud reviews, the company Itabus has the highest Wi‑Fi rating with a score of 3.1.
Which company has the most on-time service from Pisa to Milano?
According to Busbud traveller reviews, the most punctual company on this route is Trenitalia, with a punctuality rating of 4.6 out of 5 stars.
Which company has the cleanest vehicles from Pisa to Milano?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is Trenitalia, with a cleanliness rating of 4.7 out of 5 stars.
Find the cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Milano was searched and found on Jun 9, 2026 with a price of $37To save money and make sure you have the best seat, it's a good idea to buy your bus and train tickets from Pisa to Milano, as early as possible.
You can expect to pay between $37 and $110 for a bus or train ticket from Pisa to Milano based on the past 2 days. You can expect to find the lowest price for this trip at $37 on 2026-06-09.
Usually Trenitalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
