How much is the train ticket from Santander to Madrid?

The cheapest train tickets from Santander to Madrid start at $46. The average price for this train route is around $76. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.

How long is the train ride from Santander to Madrid?

The average train trip from Santander to Madrid takes 4h 16m and covers 333 km. The quickest train gets you there in 4h 16m and is operated by Renfe .

Which train operators serve the Santander to Madrid route?

Several major train operators serve this route, with 1 trains available per day.

What are the earliest and latest departure times for the train from Santander to Madrid?

The earliest train from Santander to Madrid departs at 1:58pm. The latest train departs at 7:00pm.

Train Santander to Madrid from $51

Next train departures

Next departures for Santander to Madrid on December 14
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	4:00pm	Santander	4h 31m	8:31pm	Madrid-Chamartin	Cheapest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	Fastest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	4:00pm	Santander	4h 31m	8:31pm	Madrid-Chamartin	No tags

Next departures for Santander to Madrid on December 15
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	7:00pm	Santander	4h 24m	11:24pm	Madrid-Chamartin	Cheapest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	Fastest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	7:00pm	Santander	4h 24m	11:24pm	Madrid-Chamartin	No tags

Next departures for Santander to Madrid on December 16
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	7:00pm	Santander	4h 24m	11:24pm	Madrid-Chamartin	Cheapest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	Fastest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	7:00pm	Santander	4h 24m	11:24pm	Madrid-Chamartin	No tags

Next departures for Santander to Madrid on December 17
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	7:00pm	Santander	4h 24m	11:24pm	Madrid-Chamartin	Cheapest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	Fastest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	7:00pm	Santander	4h 24m	11:24pm	Madrid-Chamartin	No tags

Next departures for Santander to Madrid on December 18
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	7:00pm	Santander	4h 24m	11:24pm	Madrid-Chamartin	Cheapest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	Fastest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	7:00pm	Santander	4h 24m	11:24pm	Madrid-Chamartin	No tags

Next departures for Santander to Madrid on December 19
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	7:00pm	Santander	4h 24m	11:24pm	Madrid-Chamartin	Cheapest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	Fastest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	7:00pm	Santander	4h 24m	11:24pm	Madrid-Chamartin	No tags

Next departures for Santander to Madrid on December 20
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	CheapestFastest
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags
Train	1:58pm	Santander	4h 16m	6:14pm	Madrid-Chamartin	No tags

Last refresh of the prices: Today at 1:02 AM CET.

Compare 3 ways to go from Santander to Madrid

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Madrid. The journey takes about 4 hours 20 minutes, and with fares starting at just $28, it presents an excellent value for a comfortable ride.

17carpool per day

4h 20mAverage Duration

339 kmDistance

14kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$61 - $252	Average Duration5h 40m	CO₂ emissions 8kg CO₂e
Train	Average Price$46 - $166	Average Duration4h 16m	CO₂ emissions 8kg CO₂e
Carpool	Average Price$28 - $77	Average Duration4h 20m	CO₂ emissions 14kg CO₂e

Where are the popular train stations and stops in Santander and Madrid?

Santander

A
Calle Navas de Tolosa, 2
Calle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
Visit page

Madrid

A
Madrid-Chamartin
C. de la Hiedra, 5, 28036 Madrid, Spain
Visit page
B
Madrid Puerta De Atocha
Madrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
Visit page
C
Madrid-Príncipe Pio
Príncipe Pío, 28008 Madrid, Spain
Visit page
D
Madrid-Barajas Airport
Visit page
E
Nuevos Ministerios
Estación de Nuevos Ministerios, 28046 Madrid, Spain

Train companies

Renfe

4/5926 reviews

Staff4.6

Timeliness4.1

Cleanliness4.5

Wifi3.1

Based on 926 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the staff and the seats but often complained with the WiFi. Renfe ticket prices on this trip start at $46

ES train and bus companies:Amtrak, Trenitalia, Renfe, VIA Rail Canada, FlixTrain, Amtrak Acela, NS Nederlandse Spoorwegen

Frequently asked questions about travelling from Santander to Madrid by train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the train ticket from Santander to Madrid?
The cheapest train tickets from Santander to Madrid start at $46. The average price for this train route is around $76. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Santander to Madrid?
The average train trip from Santander to Madrid takes 4h 16m and covers 333 km. The quickest train gets you there in 4h 16m and is operated by Renfe.
Which train operators serve the Santander to Madrid route?
Several major train operators serve this route, with 1 trains available per day.
What are the earliest and latest departure times for the train from Santander to Madrid?
The earliest train from Santander to Madrid departs at 1:58pm. The latest train departs at 7:00pm.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-12

$61

12-13

$81

Today

$61

12-15

$61

12-16

$51

12-17

$51

12-18

$51

12-19

$61

The cheapest trip from Santander to Madrid was searched and found on Dec 16, 2025 with a price of $51

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Santander to Madrid, as early as possible.

You can expect to pay from $51 to $109 for a train ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at $51 which is on 2025-12-16.