Bus and Train from Santander to Madrid: Tickets & Schedules

Next available departures

Next departures for Santander to Madrid on June 16
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
RENFE Alvia
Santander
Madrid-ChamartinCheapest
RENFE Alvia
Santander
Madrid-ChamartinFastest
ALSA Supra
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4No tags
RENFE Alvia
Santander
Madrid-ChamartinNo tags
ALSA Supra
Santander (Estacion de Autobuses)
Avenida de América MetroNo tags

Last refresh of the prices: Today at 12:46 PM CEST.

Compare 2 ways to go from Santander to Madrid

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Madrid. The journey takes about 4 hours 24 minutes, and with fares starting at just CHF 21, it presents an excellent value for a comfortable ride.

1train per day
4h 24mAverage Duration
333 kmDistance
8kgCO₂ emissions
Bus
Average PriceCHF 40 - CHF 62Average Duration5h 30m
8kg CO₂e
Train
Average PriceCHF 21 - CHF 85Average Duration4h 24m
8kg CO₂e

Frequently asked questions about travelling from Santander to Madrid by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is a ticket from Santander to Madrid?

    The cheapest tickets from Santander to Madrid start at CHF 21. The average price for this route is around CHF 42. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.

  2. How long is the ride from Santander to Madrid?

    The average trip duration from Santander to Madrid is 4h 57m, covering a distance of 334 km. The quickest vehicle can get you there in 4h 16m and is operated by Renfe.

  3. Which companies service the Santander to Madrid route?

    Several major companies operate on this route with 6 trips available per day, including services from ALSA, FlixBus, Renfe.

  4. What is the earliest and latest departure time from Santander to Madrid?

    The earliest trip from Santander to Madrid departs at 12:45am. And the latest trip departs at 7:20pm.

  5. What are the CO₂ emissions for the trip from Santander to Madrid?

    A trip from Santander to Madrid generates an estimated 8.3254875 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best company from Santander to Madrid?

    According to Busbud customers, the highest-rated company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 62253 reviews.

  7. Which company has the best Wi-Fi from Santander to Madrid?

    Based on Busbud reviews, the company ALSA has the highest Wi‑Fi rating with a score of 3.5.

  8. Which company has the most on-time service from Santander to Madrid?

    According to Busbud traveller reviews, the most punctual company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.

  9. Which company has the cleanest vehicles from Santander to Madrid?

    According to Busbud traveller reviews, the company with the cleanest vehicles on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.

Find the cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-13
CHF 35
06-14
CHF 39
Today
CHF 39
06-16
CHF 35
06-17
CHF 34
06-18
CHF 35
06-19
CHF 34
06-20
CHF 35
busbud logoThe cheapest trip from Santander to Madrid was searched and found on Jun 17, 2026 with a price of CHF 34

To save money and make sure you have the best seat, it's a good idea to buy your bus and train tickets from Santander to Madrid, as early as possible.

You can expect to pay between CHF 34 and CHF 82 for a bus or train ticket from Santander to Madrid based on the past 2 days. You can expect to find the lowest price for this trip at CHF 34 on 2026-06-17.

Usually ALSA will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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