Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Santander (Estacion de Autobuses) | Avenida de América Metro | Cheapest | |||||
| Santander (Estacion de Autobuses) | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Fastest | |||||
| Santander (Estacion de Autobuses) | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | No tags | |||||
| Santander (Estacion de Autobuses) | Avenida de América Metro | No tags | |||||
 | Santander (Estacion de Autobuses) | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | No tags |
Last refresh of the prices: Today at 3:27 AM CEST.
Compare 2 ways to go from Santander to Madrid
Among the sustainable travel choices, the Train stands out as a good way to reach Madrid. The journey takes about 4 hours 24 minutes, and with fares starting at just $37, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santander and Madrid?
Stops in Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
- C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Stops in Madrid
- AC. de la Hiedra, 5, 28036 Madrid, Spain
- BMadrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
- CPríncipe Pío, 28008 Madrid, Spain
- E
Nuevos Ministerios
Estación de Nuevos Ministerios, 28046 Madrid, Spain - FPlaza Moncloa, 671, 28008 Madrid, Spain
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Frequently asked questions about travelling from Santander to Madrid by bus or train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is a ticket from Santander to Madrid?
The cheapest tickets from Santander to Madrid start at $37. The average price for this route is around $67. Busbud recommends booking your tickets in advance for a better chance of getting the lowest possible price.
How long is the ride from Santander to Madrid?
The average trip duration from Santander to Madrid is 4h 57m, covering a distance of 332 km. The quickest vehicle can get you there in 4h 16m and is operated by Renfe.
Which companies service the Santander to Madrid route?
What is the earliest and latest departure time from Santander to Madrid?
The earliest trip from Santander to Madrid departs at 12:45am. And the latest trip departs at 7:20pm.
What are the CO₂ emissions for the trip from Santander to Madrid?
A trip from Santander to Madrid generates an estimated 8.2813125 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best company from Santander to Madrid?
According to Busbud customers, the highest-rated company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61661 reviews.
Which company has the best Wi-Fi from Santander to Madrid?
Based on Busbud reviews, the company ALSA has the highest Wi‑Fi rating with a score of 3.5.
Which company has the most on-time service from Santander to Madrid?
According to Busbud traveller reviews, the most punctual company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which company has the cleanest vehicles from Santander to Madrid?
According to Busbud traveller reviews, the company with the cleanest vehicles on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.
Find the cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Madrid was searched and found on Apr 15, 2026 with a price of $31To save money and make sure you have the best seat, it's a good idea to buy your bus and train tickets from Santander to Madrid, as early as possible.
You can expect to pay between $31 and $99 for a bus or train ticket from Santander to Madrid based on the past 2 days. You can expect to find the lowest price for this trip at $31 on 2026-04-18.
Usually ALSA will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
