Bus and Train from Santander to Madrid: Tickets & Schedules

Next available departures

Next departures for Santander to Madrid on June 12
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
RENFE Alvia
Santander
Madrid-ChamartinCheapest
RENFE Alvia
Santander
Madrid-ChamartinFastest
RENFE Alvia
Santander
Madrid-ChamartinNo tags
RENFE Alvia
Santander
Madrid-ChamartinNo tags

Last refresh of the prices: Today at 10:48 AM CEST.

Compare 2 ways to go from Santander to Madrid

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Madrid. The journey takes about 4 hours 24 minutes and with fares starting at just R$135, it presents an excellent value for a comfortable ride.

1train per day
4h 24mAverage Duration
206 milesDistance
8kgCO₂ emissions
Bus
Average PriceR$261 - R$402Average Duration5h 30m
8kg CO₂e
Train
Average PriceR$135 - R$550Average Duration4h 24m
8kg CO₂e

Frequently asked questions about traveling from Santander to Madrid by bus or train

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is a ticket from Santander to Madrid?

    The cheapest tickets from Santander to Madrid start from R$135. The average price for this route is around R$269. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the ride from Santander to Madrid?

    The average trip duration from Santander to Madrid is 4h 57m, covering a distance of 207 miles (334 km). The quickest vehicle can get you there in 4h 16m and is operated by Renfe.

  3. Which companies service the Santander to Madrid route?

    Several major companies operate on this route with 6 trips available per day, including services from ALSA, FlixBus, Renfe.

  4. What is the earliest and latest departure time from Santander to Madrid?

    The earliest trip departs from Santander to Madrid at 12:45am. And the latest trip departs at 7:20pm.

  5. What are the CO₂ emissions for the trip from Santander to Madrid?

    A trip from Santander to Madrid generates an estimated 8.3254875 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best company from Santander to Madrid?

    According to Busbud customers, the highest-rated company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 62101 reviews.

  7. Which company has the best Wi-Fi from Santander to Madrid?

    Based on reviews on Busbud, the company ALSA has the best Wi-Fi rating with a score of 3.5.

  8. Which company has the most timely service from Santander to Madrid?

    According to Busbud traveler reviews, the most timely company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.

  9. Which company has the cleanest vehicles from Santander to Madrid?

    According to Busbud traveler reviews, the company with the cleanest vehicles on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses and trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/09
R$249
06/10
R$248
Today
R$225
06/12
R$231
06/13
R$225
06/14
R$225
06/15
R$225
06/16
R$151
busbud logoThe cheapest trip from Santander to Madrid was searched and found on Jun 16, 2026 with a price of R$151

To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Santander to Madrid, as early as possible.

You can expect to pay from R$151 to R$422 for a bus or train ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at R$151 which is on 2026-06-16.

Usually ALSA will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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