Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Santander (Estacion de Autobuses) | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Cheapest | |||||
 | Santander | Madrid-Chamartin | Fastest | |||||
 | Santander (Estacion de Autobuses) | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | No tags | |||||
| Santander | Madrid-Chamartin | No tags | |||||
| Santander (Estacion de Autobuses) | Avenida de América Metro | No tags |
Last refresh of the prices: Today at 9:16 AM CEST.
Compare 2 ways to go from Santander to Madrid
Among the sustainable travel choices, the Train stands out as a good way to reach Madrid. The journey takes about 4 hours 24 minutes and with fares starting at just ¥4,170, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santander and Madrid?
Stops in Santander
- A
Calle Navas de Tolosa, 2
Calle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain - C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Stops in Madrid
- A
Madrid-Chamartin
C. de la Hiedra, 5, 28036 Madrid, Spain - B
Madrid Puerta De Atocha
Madrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain - C
Madrid-Príncipe Pio
Príncipe Pío, 28008 Madrid, Spain - E
Nuevos Ministerios
Estación de Nuevos Ministerios, 28046 Madrid, Spain - F
Moncloa
Plaza Moncloa, 671, 28008 Madrid, Spain
Compare companies
Frequently asked questions about traveling from Santander to Madrid by bus or train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is a ticket from Santander to Madrid?
The cheapest tickets from Santander to Madrid start from ¥4,170. The average price for this route is around ¥8,316. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the ride from Santander to Madrid?
The average trip duration from Santander to Madrid is 4h 57m, covering a distance of 207 miles (334 km). The quickest vehicle can get you there in 4h 16m and is operated by Renfe.
Which companies service the Santander to Madrid route?
What is the earliest and latest departure time from Santander to Madrid?
The earliest trip departs from Santander to Madrid at 12:45am. And the latest trip departs at 7:20pm.
What are the CO₂ emissions for the trip from Santander to Madrid?
A trip from Santander to Madrid generates an estimated 8.3254875 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best company from Santander to Madrid?
According to Busbud customers, the highest-rated company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 62253 reviews.
Which company has the best Wi-Fi from Santander to Madrid?
Based on reviews on Busbud, the company ALSA has the best Wi-Fi rating with a score of 3.5.
Which company has the most timely service from Santander to Madrid?
According to Busbud traveler reviews, the most timely company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which company has the cleanest vehicles from Santander to Madrid?
According to Busbud traveler reviews, the company with the cleanest vehicles on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Madrid was searched and found on Jun 16, 2026 with a price of ¥4,635To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Santander to Madrid, as early as possible.
You can expect to pay from ¥4,635 to ¥15,337 for a bus or train ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at ¥4,635 which is on 2026-06-16.
Usually ALSA will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
