Train tickets from Brussels to Prague

Next train departures

Next departures for Brussels to Prague on November 22
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
InterCity + S-Bahn + Regional-Express + Deutsche Bahn ICE + EuroCity Train
Train
Brussels Central Train Station
Hlavní nádražíCheapest
InterCity + Regional-Express + EuroCity Train
Train
Brussels Central Train Station
Hlavní nádražíFastest
InterCity + Regional-Express + EuroCity Train
Train
Brussels Central Train Station
Hlavní nádražíNo tags
InterCity + S-Bahn + Regional-Express + Deutsche Bahn ICE + EuroCity Train
Train
Brussels Central Train Station
Hlavní nádražíNo tags
InterCity + Regional-Express + EuroCity Train
Train
Brussels Central Train Station
Hlavní nádražíNo tags

Last refresh of the prices: Yesterday at 6:27 PM CET.

Compare 2 ways to go from Brussels to Prague

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Prague. The journey takes about 19 hours 15 minutes, and with fares starting at just $64, it presents an excellent value for a comfortable ride.

35bus per day
19h 15mAverage Duration
718 kmDistance
18kgCO₂ emissions
Average Price$64 - $318Average Duration19h 15m
18kg CO₂e
Average Price$92 - $445Average Duration14h 36m
17kg CO₂e

Frequently asked questions about travelling from Brussels to Prague by train

  1. How much does a cheap train ticket from Brussels to Prague cost?

    The average train ticket price from Brussels to Prague is $202. The best way to find cheap train tickets from Brussels to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the trip from Brussels to Prague?

    A train trip between Brussels and Prague is around 14h 36m, although the fastest train will take about 11h 3m. This is the time it takes to travel the 719 km that separates the two cities.

  3. How many daily trains are there between Brussels and Prague?

    The number of trains from Brussels to Prague can differ depending on the day of the week. On average, there are 5. Some trains are direct while others include transferring trains. Simplify your train trip from Brussels to Prague by comparing and selecting the train that fits your travel style and budget on Busbud.

  4. What are the departure and arrival stations for a train from Brussels to Prague?

    Trains travelling between Brussels and Prague leave from Brux-Nord or Brussels South (Gare du Midi) and arrive at Hlavní nádraží, Florenc, PRG Airport.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-19
$361
11-20
No data
Today
$328
11-22
No data
11-23
No data
11-24
$223
11-25
No data
11-26
$256
busbud logoThe cheapest trip from Brussels to Prague was searched and found on Nov 24, 2025 with a price of $223

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague, as early as possible.

You can expect to pay from $223 to $1,630 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $223 which is on 2025-11-24.

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