Next departures from Brussels to Prague on 23 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
InterCity + Deutsche Bahn ICE + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
Cheapest
InterCity + Deutsche Bahn ICE + S-Bahn + EuroCity Train
Train
Brussels Central Train Station
Hlavní nádraží
Fastest
InterCity + Deutsche Bahn ICE + S-Bahn + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
No tags
InterCity + Deutsche Bahn ICE + S-Bahn + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
No tags
InterCity + Deutsche Bahn ICE + S-Bahn + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
No tags
Next departures from Brussels to Prague on 24 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
InterCity + Regional-Express + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
Cheapest
InterCity + Regional-Express + EuroCity Train
Train
Brussels Central Train Station
Hlavní nádraží
Fastest
Train
Brussels South/Midi Train Station
Hlavní nádraží
No tags
InterCity + Regional-Express + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
No tags
Train
Brussels South/Midi Train Station
Hlavní nádraží
No tags
Next departures from Brussels to Prague on 25 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
InterCity + Regional-Express + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
CheapestFastest
InterCity + Regional-Express + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
No tags
InterCity + Regional-Express + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
No tags
InterCity + Regional-Express + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
No tags
InterCity + Regional-Express + EuroCity Train
Train
Schaarbeek
Hlavní nádraží
No tags
Next departures from Brussels to Prague on 26 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
Brussels South/Midi Train Station
Hlavní nádraží
CheapestFastest
Train
Brussels South/Midi Train Station
Hlavní nádraží
No tags
Train
Brussels South/Midi Train Station
Hlavní nádraží
No tags
Train
Brussels South/Midi Train Station
Hlavní nádraží
No tags
Train
Brussels South/Midi Train Station
Hlavní nádraží
No tags
Next departures from Brussels to Prague on 28 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
Brussels South/Midi Train Station
Hlavní nádraží
CheapestFastest
Train
Brussels South/Midi Train Station
Hlavní nádraží
No tags
Train
Brussels South/Midi Train Station
Hlavní nádraží
No tags
Train
Brussels South/Midi Train Station
Hlavní nádraží
No tags
Train
Brussels South/Midi Train Station
Hlavní nádraží
No tags
Last refresh of the prices: Yesterday at 18:27 CET.
Compare 2 ways to travel from Brussels to Prague
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Prague. The journey takes about 19 hours 15 minutes and with fares starting at just £35, it presents an excellent value for a comfortable ride.
Frequently asked questions about travelling from Brussels to Prague by train
How much does a cheap train ticket from Brussels to Prague cost?
The average train ticket price from Brussels to Prague is £109. The best way to find cheap train tickets from Brussels to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Brussels to Prague?
A train trip between Brussels and Prague is around 14h 36m, although the fastest train will take about 11h 3m. This is the time it takes to travel the 446 miles that separates the two cities.
How many daily train are there between Brussels and Prague?
The number of trains from Brussels to Prague can differ depending on the day of the week. On average, there are 5. Some trains are direct while others include transferring trains. Simplify your train trip from Brussels to Prague by comparing and selecting the train that fits your travel style and budget on Busbud.
What are the departure and arrival stations for a train from Brussels to Prague?
Trains travelling between Brussels and Prague leave from Brux-Nord or Brussels South (Gare du Midi) and arrive at Hlavní nádraží, Florenc, PRG Airport.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
19/11
£196
20/11
No data
Today
£178
22/11
No data
23/11
No data
24/11
£121
25/11
No data
26/11
£139
The cheapest trip from Brussels to Prague was searched and found on 24 Nov 2025 with a price of £121
To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague as early as possible.
You can expect to pay from £121 to £884 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at £121, which is on 2025-11-24.