Among the sustainable travel choices, the bus stands out as the good way to reach Prague. The journey takes about 19 hours 15 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.
Frequently asked questions about traveling from Brussels to Prague by train
How much does a train ticket from Brussels to Prague cost?
The average train ticket price from Brussels to Prague is $140. The best way to find train tickets from Brussels to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Brussels to Prague?
A train trip between Brussels and Prague is around 14h 36m, although the fastest train will take about 11h 3m. This is the time it takes to travel the 446 miles that separates the two cities.
How many daily trains are there between Brussels and Prague?
The number of trains from Brussels to Prague can differ depending on the day of the week. On average, there are 5. Some trains are direct while others have layovers. Simplify your train trip from Brussels to Prague by comparing and selecting the train that fits your travel style and budget on Busbud.
What are the departure and arrival stations for a train from Brussels to Prague?
Trains traveling between Brussels and Prague leave from Brux-Nord or Brussels South (Gare du Midi) and arrive at Hlavní nádraží, Florenc, PRG Airport.
What are the best sights and things to do in Prague?
Once in Prague, you can explore the city. The top sights and things to do are Karlův most (Charles Bridge), Old Town City Hall & Astronomical Clock, Prague Zoo, KGB Museum, Catch local acts.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$155
11/18
No data
Today
$250
11/20
No data
11/21
$179
11/22
No data
11/23
No data
11/24
$84
The cheapest trip from Brussels to Prague was searched and found on Nov 24, 2025 with a price of $84
To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague, as early as possible.
You can expect to pay from $84 to $1,130 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $84 which is on 2025-11-24.
The cheapest trip from Brussels to Prague was searched and found on Nov 24, 2025 with a price of $84
