Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Indianapolis Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
Greyhound + FlixBus | Bus | Indianapolis Northeast | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Indianapolis Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
| Bus | Indianapolis Bus Station | Tupelo (Brothers Quick Stop) | No tags | ||||
Greyhound + FlixBus | Bus | Downtown Transit Center | Tupelo (Brothers Quick Stop) | No tags |
Get from Indianapolis to Tupelo
The journey takes about 17 hours 55 minutes, and with fares starting at just £85, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling by bus from Indianapolis to Tupelo
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Indianapolis to Tupelo?
The cheapest coach tickets from Indianapolis to Tupelo start from £85. The average price for this route is around £106. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Indianapolis to Tupelo?
The average bus journey time from Indianapolis to Tupelo is 17h 55m, covering a distance of 406 miles. The fastest bus can take you there in 14h 20m and is operated by FlixBus.
Which bus companies service the Indianapolis to Tupelo route?
What is the earliest and latest departure time for the bus from Indianapolis to Tupelo?
The earliest bus departs from Indianapolis to Tupelo at 03:15. And the latest bus departs at 23:30.
What are the CO₂ emissions for the bus trip from Indianapolis to Tupelo?
A bus journey from Indianapolis to Tupelo produces an estimated 16 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Indianapolis to Tupelo?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which company has the best Wi-Fi from Indianapolis to Tupelo?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Indianapolis to Tupelo?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Indianapolis to Tupelo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Tupelo was searched and found on 2 Jan 2026 with a price of £101To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Tupelo as early as possible.
