Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
![]() | Bus | Indianapolis Bus Station | Tupelo (Brothers Quick Stop) | ||||
Greyhound + FlixBus | Bus | Indianapolis Northeast | Tupelo (Brothers Quick Stop) | ||||
Greyhound + FlixBus | Bus | Downtown Transit Center | Tupelo (Brothers Quick Stop) | ||||
![]() | Bus | Indianapolis Bus Station | Tupelo (Brothers Quick Stop) | ||||
FlixBus + Greyhound | Bus | Downtown Transit Center | Tupelo (Brothers Quick Stop) |
Get from Indianapolis to Tupelo
The journey takes about 17 hours 15 minutes and with fares starting at just ARS 204,945, it presents an excellent value for a comfortable ride.
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Indianapolis to Tupelo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Indianapolis to Tupelo?
The cheapest bus tickets from Indianapolis to Tupelo start from ARS 204,945. The average price for this route is around ARS 249,252. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Indianapolis to Tupelo?
The average bus trip duration from Indianapolis to Tupelo is 17h 15m, covering a distance of 406 miles (655 km). The quickest bus can get you there in 15h 30m and is operated by Greyhound.
Which bus companies service the Indianapolis to Tupelo route?
Several major bus companies operate on this route with 5 buses available per day.
What is the earliest and latest departure time for the bus from Indianapolis to Tupelo?
The earliest bus departs from Indianapolis to Tupelo at 3:15am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Indianapolis to Tupelo?
A bus trip from Indianapolis to Tupelo generates an estimated 16.3617 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.





