Bus Tickets from Indianapolis to Tupelo

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TomorrowJul 8
WedJul 9
ThuJul 10
from $108
FriJul 11
SatJul 12
SunJul 13
MonJul 14
TueJul 15

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 10 at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: July 11 at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 10 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: July 11 at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 10 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: July 10 at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 10 at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: July 11 at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 10 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: July 11 at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Indianapolis to Tupelo: Trip Overview

Average ticket price$144
Average bus trip duration19h
Number of daily buses6
Earliest bus departure3:35am
Distance407 miles (655 km)
Latest bus departure11:30pm

Indianapolis to Tupelo Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Tupelo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Indianapolis to Tupelo will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Indianapolis to Tupelo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Indianapolis - Tupelo

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/05
$113
07/06
No data
Today
No data
07/08
No data
07/09
No data
07/10
$101
07/11
No data
07/12
$121
busbud logoThe cheapest trip from Indianapolis to Tupelo was searched and found on Jul 10, 2025 with a price of $101

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Tupelo, as early as possible.

You can expect to pay from $101 to $138 for a bus ticket from Indianapolis to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at $101 which is on 2025-07-10.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Indianapolis to Tupelo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Indianapolis to Tupelo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Indianapolis to Tupelo that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to Tupelo while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Tupelo

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