Find coaches from La Spezia to Palermo

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Today8 Jul
from US$144
Tomorrow9 Jul
from US$139
Thu10 Jul
Fri11 Jul
Sat12 Jul
Sun13 Jul
Mon14 Jul
Tue15 Jul

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 9 July at
    Departure city: La Spezia
    Departure location: La Spezia (Via Carducci)
    Arrival time: 10 July at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: 9 July at
    Departure city: La Spezia
    Departure location: La Spezia (Via Carducci)
    Arrival time: 10 July at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

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Compare 2 ways to travel from La Spezia to Palermo

Bus
Average priceUS$169 - US$219Average duration22h 10m
18kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average priceUS$113 - US$113Average duration13h 10m
31kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the bus from La Spezia to Palermo

Among the sustainable travel choices, the bus stands out as a good way to reach Palermo. The journey takes about 22 hours 10 minutes and with fares starting at just US$169, it presents an excellent value for a comfortable ride.

2bus per day
22h 10mAverage duration
US$169Cheapest ticket
18kgCO₂ emissions

Bus La Spezia to Palermo: Trip Overview

Average ticket priceUS$169
Average bus trip duration22h 10m
Number of daily buses2
Earliest bus departure12:10
Distance453 miles
Latest bus departure17:55

La Spezia to Palermo Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from La Spezia to Palermo.

We make sure you can find a bus service from La Spezia to Palermo from the most reliable bus companies operating this trip.

Discover how much the bus trip from La Spezia to Palermo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip La Spezia - Palermo

  1. How much does a bus ticket from La Spezia to Palermo cost?

    The bus ticket price from La Spezia to Palermo starts at US$169. The best way to find cheap bus tickets from La Spezia to Palermo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from La Spezia to Palermo?

    The average travel time between La Spezia and Palermo is around 22h 10m, although the fastest bus will take about 22h 10m. This is the time it takes to travel the 453 miles that separates the two cities.

  3. How many daily bus connections are there between La Spezia and Palermo?

    The number of buses from La Spezia to Palermo can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from La Spezia to Palermo by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from La Spezia to Palermo?

    When taking the bus from La Spezia to Palermo, you can travel comfortably and safely with FlixBus.

  5. What are the departure and arrival stations when taking the bus from La Spezia to Palermo?

    Buses travelling between La Spezia and Palermo leave from Piazzale Rosselli FS Stazione or Fermata dell'autobus La Spezia and arrive at Terminal Bus Palermo, Palermo Airport, Piazza Cairoli.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/07
No data
07/07
US$172
Today
US$141
09/07
US$136
10/07
No data
11/07
No data
12/07
No data
13/07
No data
busbud logoThe cheapest trip from La Spezia to Palermo was searched and found on 9 Jul 2025 with a price of US$136

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Spezia to Palermo as early as possible.

You can expect to pay from US$136 to US$202 for a bus ticket from La Spezia to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at US$136, which is on 2025-07-09.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from La Spezia to Palermo but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from La Spezia to Palermo, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from La Spezia to Palermo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from La Spezia to Palermo while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to La Spezia by bus?

Bus from La Spezia to Palermo

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