Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Bus Palermo | Siena Train Station | CheapestFastest | ||||
| Bus | Terminal Bus Palermo | Siena Train Station | No tags | ||||
| Bus | Terminal Bus Palermo | Viale Toselli (Penny Market) | No tags | ||||
| Bus | Terminal Bus Palermo | Viale Toselli (Penny Market) | No tags | ||||
| Bus | Terminal Bus Palermo | Piazza Gramsci | No tags |
Last refresh of the prices: Yesterday at 04:36 CEST.
Get from Palermo to Siena
The journey takes about 19 hours 50 minutes, and with fares starting at just SGD 89, it presents an excellent value for a comfortable ride.
Where are the popular stops in Palermo and Siena?
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Stops in Siena
- APiazza Antonio Gramsci, 53100 Siena SI, Italy
- B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy - C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy - D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy - E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy - F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy
Compare bus companies
Based on 12512 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at SGD 89
Frequently asked questions about travelling by bus from Palermo to Siena
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Palermo to Siena?
The cheapest coach tickets from Palermo to Siena start from SGD 89. The average price for this route is around SGD 119. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Palermo to Siena?
The average bus journey time from Palermo to Siena is 19h 50m, covering a distance of 375 miles. The fastest bus can take you there in 16h 20m and is operated by FlixBus.
Which bus companies service the Palermo to Siena route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Palermo to Siena?
The earliest bus departs from Palermo to Siena at 15:25. And the latest bus departs at 21:10.
What are the CO₂ emissions for the bus trip from Palermo to Siena?
A bus journey from Palermo to Siena produces an estimated 15.1166 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Siena was searched and found on 22 Apr 2026 with a price of SGD 97To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Siena as early as possible.
What's the cheapest way to go from Palermo to Siena?
The Bus is the cheapest travel choice for this destination
