Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Parcheggio Via Pietransantina | Prague (Central Bus Station Florenc) | CheapestFastest | ||||
| Bus | Parcheggio Via Pietransantina | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Prague (Main Railway Station) | No tags |
Last refresh of the prices: Yesterday at 19:02 CEST.
Get from Pisa to Prague
The journey takes about 20 hours 45 minutes, and with fares starting at just £65, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Prague?
Stops in Pisa
- AVia Pietrasantina, 56123 Pisa PI
- C
Piazza della Stazione
Piazza della Stazione, 1, 56125 Pisa PI, Italy
Stops in Prague
- AChlumecká, 198 00 Praha 20, Czech Republic
- BAviatická, 161 08, Praha 6, Czechia
- C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - DKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- ETomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- F300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
Based on 12474 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at £65
Frequently asked questions about travelling by bus from Pisa to Prague
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Pisa to Prague?
The cheapest coach tickets from Pisa to Prague start from £65. The average price for this route is around £97. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Pisa to Prague?
The average bus journey time from Pisa to Prague is 20h 45m, covering a distance of 474 miles. The fastest bus can take you there in 16h 5m and is operated by FlixBus.
Which bus companies service the Pisa to Prague route?
Several major bus companies operate on this route with 12 buses available per day.
What is the earliest and latest departure time for the bus from Pisa to Prague?
The earliest bus departs from Pisa to Prague at 06:25. And the latest bus departs at 22:00.
What are the CO₂ emissions for the bus trip from Pisa to Prague?
A bus journey from Pisa to Prague produces an estimated 19.075575 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Prague was searched and found on 16 Apr 2026 with a price of £64To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Prague as early as possible.
You can expect to pay from £64 to £129 for a bus ticket from Pisa to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at £64, which is on 2026-04-16.
