Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Parcheggio Via Pietransantina | Prague (Central Bus Station Florenc) | CheapestFastest | ||||
| Bus | Parcheggio Via Pietransantina | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Prague (Main Railway Station) | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Prague (Main Railway Station) | No tags | ||||
| Bus | Parcheggio Via Pietransantina | Prague (Main Railway Station) | No tags |
Last refresh of the prices: Yesterday at 8:02 AM CEST.
Get from Pisa to Prague
The journey takes about 21 hours 20 minutes and with fares starting at just $84, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Prague?
Stops in Pisa
- AVia Pietrasantina, 56123 Pisa PI
- C
Piazza della Stazione
Piazza della Stazione, 1, 56125 Pisa PI, Italy
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- B
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - CChlumecká, 198 00 Praha 20, Czech Republic
- DKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- ETomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- F300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Pisa to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pisa to Prague?
The cheapest bus tickets from Pisa to Prague start from $84. The average price for this route is around $100. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pisa to Prague?
The average bus trip duration from Pisa to Prague is 21h 20m, covering a distance of 478 miles (771 km). The quickest bus can get you there in 16h 5m and is operated by FlixBus.
Which bus companies service the Pisa to Prague route?
Several major bus companies operate on this route with 9 buses available per day.
What is the earliest and latest departure time for the bus from Pisa to Prague?
The earliest bus departs from Pisa to Prague at 6:25am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Pisa to Prague?
A bus trip from Pisa to Prague generates an estimated 19.253974999999997 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Prague was searched and found on Apr 4, 2026 with a price of $114To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Prague, as early as possible.
