Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Jacksonville Bus Station | Florence, SC | CheapestFastest |
Last refresh of the prices: Last Wednesday at 13:15 EDT.
Compare 2 ways to travel from Jacksonville to Florence
Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 5 hours 35 minutes and with fares starting at just €40, it presents an excellent value for a comfortable ride.
Where are the popular stops in Jacksonville and Florence?
Stops in Jacksonville
- A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA - B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about travelling by bus from Jacksonville, FL to Florence, SC, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Jacksonville to Florence?
The cheapest coach tickets from Jacksonville to Florence start from €40. The average price for this route is around €47. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Jacksonville to Florence?
The average bus journey time from Jacksonville to Florence is 5h 35m, covering a distance of 466 km. The fastest bus can take you there in 5h 10m and is operated by FlixBus.
Which bus companies service the Jacksonville to Florence route?
What is the earliest and latest departure time for the bus from Jacksonville to Florence?
The earliest bus departs from Jacksonville to Florence at 08:15. And the latest bus departs at 18:30.
What are the CO₂ emissions for the bus trip from Jacksonville to Florence?
A bus journey from Jacksonville to Florence produces an estimated 11.63445 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Jacksonville to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12791 reviews.
Which company has the best Wi-Fi from Jacksonville to Florence?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Jacksonville to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Florence, SC, US was searched and found on 10 Jun 2026 with a price of €34To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Florence, SC, US as early as possible.
You can expect to pay from €34 to €92 for a bus ticket from Jacksonville, FL to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at €37, which is on 2026-06-17.
What's the cheapest way to go from Jacksonville, FL to Florence, SC, US?
The Bus is the cheapest travel choice for this destination
