How much is the bus ticket from Jacksonville to Florence?

The cheapest bus tickets from Jacksonville to Florence start from PLN 169. The average price for this route is around PLN 228. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Jacksonville to Florence?

The average bus trip duration from Jacksonville to Florence is 5h 10m, covering a distance of 289 miles (466 km). The quickest bus can get you there in 5h 10m and is operated by FlixBus .

Which bus companies service the Jacksonville to Florence route?

Several major bus companies operate on this route with 1 buses available per day.

What is the earliest and latest departure time for the bus from Jacksonville to Florence?

The earliest bus departs from Jacksonville to Florence at 8:15am. And the latest bus departs at 6:30pm.

What are the CO₂ emissions for the bus trip from Jacksonville to Florence?

A bus trip from Jacksonville to Florence generates an estimated 11.6329 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus Jacksonville to Florence from PLN 142 | Refundable Tickets

Next bus departures

Next departures for Jacksonville to Florence on May 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	6:30pm	Jacksonville Bus Station	5h 35m	12:05am	Florence, SC	Cheapest
	Bus	8:15am	Jacksonville Bus Station	5h 10m	1:25pm	Bus station	Fastest

Next departures for Jacksonville to Florence on May 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	6:30pm	Jacksonville Bus Station	5h 35m	12:05am	Florence, SC	CheapestFastest

Next departures for Jacksonville to Florence on May 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	6:30pm	Jacksonville Bus Station	5h 35m	12:05am	Florence, SC	Cheapest
	Bus	8:15am	Jacksonville Bus Station	5h 10m	1:25pm	Bus station	Fastest

Last refresh of the prices: Last Monday at 12:17 AM EDT.

Compare 2 ways to go from Jacksonville to Florence

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 5 hours 10 minutes and with fares starting at just PLN 169, it presents an excellent value for a comfortable ride.

1bus per day

5h 10mAverage Duration

289 milesDistance

12kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PricePLN 169 - PLN 583	Average Duration5h 10m	CO₂ emissions 12kg CO₂e
Train	Average PricePLN 252 - PLN 665	Average Duration6h 11m	CO₂ emissions 42kg CO₂e

Where are the popular stops in Jacksonville and Florence?

Stops in Jacksonville

A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
Visit page
B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA
C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207
D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/512,634 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Valley Transit

Frequently asked questions about traveling from Jacksonville, FL to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Jacksonville to Florence?
The cheapest bus tickets from Jacksonville to Florence start from PLN 169. The average price for this route is around PLN 228. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to Florence?
The average bus trip duration from Jacksonville to Florence is 5h 10m, covering a distance of 289 miles (466 km). The quickest bus can get you there in 5h 10m and is operated by FlixBus.
Which bus companies service the Jacksonville to Florence route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Jacksonville to Florence?
The earliest bus departs from Jacksonville to Florence at 8:15am. And the latest bus departs at 6:30pm.
What are the CO₂ emissions for the bus trip from Jacksonville to Florence?
A bus trip from Jacksonville to Florence generates an estimated 11.6329 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/12

PLN 161

05/13

PLN 217

Today

PLN 202

05/15

PLN 187

05/16

PLN 217

05/17

PLN 187

05/18

No data

05/19

No data

The cheapest trip from Jacksonville, FL to Florence, SC, US was searched and found on May 12, 2026 with a price of PLN 161

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Florence, SC, US, as early as possible.

You can expect to pay from PLN 161 to PLN 217 for a bus ticket from Jacksonville, FL to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at PLN 187 which is on 2026-05-15.