Bus Tickets from Jacksonville, FL to Florence, SC

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Compare 2 ways to go from Jacksonville to Florence

Bus
Average PriceUS$62 - US$128Average Duration5h 29m
12kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$64 - US$147Average Duration6h 11m
42kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to Florence

Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 5 hours 29 minutes, and with fares starting at just US$62, it presents an excellent value for a comfortable ride.

1bus per day
5h 29mAverage Duration
US$62Cheapest ticket
12kgCO₂ emissions

Bus Jacksonville to Florence: Trip Overview

Average Ticket PriceUS$66
Average Bus Trip Duration5h 29m
Number of daily buses1
Earliest bus departure6:30pm
Distance466 km

Jacksonville to Florence Bus

With Busbud, comparing and booking tickets for a bus from Jacksonville to Florence is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Jacksonville to Florence will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Florence from Jacksonville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Jacksonville - Florence

  1. How long does it take to get to Florence from Jacksonville by bus?

    The trip from Jacksonville to Florence will take on average 5h 29m. The fastest bus on this trip will get to Florence in 5h 29m

  2. What is the distance between Jacksonville and Florence?

    It's about 472 km (293 miles) from Jacksonville to Florence.

  3. What are the departure and arrival locations for buses traveling from Jacksonville to Florence?

    Buses traveling this route start their trip at Jacksonville Amtrak Station, in Jacksonville, and end it at Florence Bus Station, in Florence.

  4. What is the cheapest way to travel from Jacksonville to Florence?

    Taking the bus is the cheapest option to travel from Jacksonville to Florence. The ticket price for this bus starts at US$62, making this your best choice for this trip.

  5. How much is the bus from Jacksonville to Florence?

    Taking the bus from Jacksonville to Florence costs on average US$66.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-11
US$58
05-12
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Today
No data
05-14
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05-15
US$53
05-16
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05-17
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05-18
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busbud logoThe cheapest trip from Jacksonville to Florence was searched and found on May 15, 2025 with a price of US$53

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville to Florence, as early as possible.

You can expect to pay from US$53 to US$58 for a bus ticket from Jacksonville to Florence based on the last 2 days. You can expect to find the cheapest price for the trip at US$53 which is on 2025-05-15.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Jacksonville to Florence.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Jacksonville to Florence, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Jacksonville to Florence.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Jacksonville to Florence.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Jacksonville to Florence?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville by bus?

Bus from Jacksonville to Florence

You can also go to Florence by train

Train from Jacksonville to Florence

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