- Brussels to Lyon buses
Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link | 
|---|---|---|---|---|---|---|---|---|
|  | Brussels-South (Gare du Midi) | Lyon - Perrache Bus Station | Cheapest | |||||
|  | Brussels-South (Gare du Midi) | Lyon - Perrache Bus Station | Fastest | |||||
|  | Brussels-South (Gare du Midi) | Lyon - Perrache Bus Station | No tags | |||||
|  | Brussels Airport | Perrache | No tags | |||||
|  | Brussels-South (Gare du Midi) | Lyon - Perrache Bus Station | No tags | 
Last refresh of the prices: Today at 9:55 AM CET.
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Compare 3 ways to travel from Brussels to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 7 hours 50 minutes and with fares starting at just US$45, it presents an excellent value for a comfortable ride.
Bus Brussels to Lyon: Trip Overview
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Brussels to Lyon Bus
Busbud helps you find a bus from Brussels to Lyon. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Brussels to Lyon.
Whether it is cheap bus tickets or more luxurious buses going to Lyon from Brussels, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Brussels and Lyon?
Frequently asked questions on the trip Brussels - Lyon
- How much does a bus ticket from Brussels to Lyon cost?- The bus ticket price from Brussels to Lyon starts at US$27. The best way to find cheap bus tickets from Brussels to Lyon is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices! 
- How long is the bus ride from Brussels to Lyon?- The average travel time between Brussels and Lyon is around 11h 40m, although the fastest bus will take about 9h 10m. This is the time it takes to travel the 569 km that separates the two cities. 
- How many daily bus connections are there between Brussels and Lyon?- The number of buses from Brussels to Lyon can differ depending on the day of the week. On average, there are 18 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Brussels to Lyon by comparing and selecting the bus that fits your travel style and budget on Busbud. 
- Which bus companies travel from Brussels to Lyon?- When taking the bus from Brussels to Lyon, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus. 
- What are the departure and arrival stations when taking the bus from Brussels to Lyon?- Buses travelling between Brussels and Lyon leave from Brussels South (Gare du Midi) or Brux-Nord and arrive at Perrache, Lyon Airport, Lyon. 
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Lyon as early as possible.
You can expect to pay from US$31 to US$162 for a bus ticket from Brussels to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at US$31, which is on 2025-11-05.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Brussels and Lyon!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Brussels to Lyon.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Brussels to Lyon.
Make a music playlist for your bus ride from Brussels to Lyon, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
What's the cheapest way to go from Brussels to Lyon?
Why choose Busbud?
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Brussels
Buses Leaving from Brussels
- Bus from Brussels to Charleroi
- Coach Brussels - Bruges
- Bus Brussels - London
- Bus from Brussels to Ghent
- Coach Brussels - Barcelona
- Bus Brussels - Amsterdam
- Bus from Brussels to Kortrijk
- Coach Brussels - Turnhout
- Bus Brussels - Mons
- Bus from Brussels to Bastogne
- Coach Brussels - Antwerp
- Bus Brussels - Hasselt
- Bus from Brussels to Arlon
- Coach Brussels - Liège
- Bus Brussels - Leuven
Buses Going to Brussels
- Bus from Charleroi to Brussels
- Coach Amsterdam - Brussels
- Bus Paris - Brussels
- Bus from Berlin to Brussels
- Coach Tours - Brussels
- Bus Cologne - Brussels
- Bus from Hasselt to Brussels
- Coach Mons - Brussels
- Bus Arlon - Brussels
- Bus from Bruges to Brussels
- Coach Liège - Brussels
- Bus Turnhout - Brussels
- Bus from Ghent to Brussels
- Coach Leuven - Brussels
- Bus Kortrijk - Brussels
Popular Buses Connecting Lyon
Buses Leaving from Lyon
- Bus from Lyon to Marseille
- Coach Lyon - Saint-Étienne
- Bus Lyon - Lens
- Bus from Lyon to Reims
- Coach Lyon - Rennes
- Bus Lyon - Auxerre
- Bus from Lyon to Strasbourg
- Coach Lyon - Orleans
- Bus Lyon - Mimizan
- Bus from Lyon to Albertville
- Coach Lyon - Mâcon
- Bus Lyon - Saint-Pierre-Quiberon
- Bus from Lyon to Le Lavandou
- Coach Lyon - Calais
- Bus Lyon - Famars
Buses Going to Lyon
- Bus from Saint-Étienne to Lyon
- Coach Nice - Lyon
- Bus Montpellier - Lyon
- Bus from Le Havre to Lyon
- Coach Brest - Lyon
- Bus Utrecht - Lyon
- Bus from Famars to Lyon
- Coach Chalon-sur-Saône - Lyon
- Bus Biarritz - Lyon
- Bus from Paris to Lyon
- Coach Pusignan - Lyon
- Bus Béziers - Lyon
- Bus from Le Puy to Lyon
- Coach Saint-Brieuc - Lyon
- Bus Toulouse - Lyon