Bus from Brussels to Prague: Tickets & Schedules

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Next bus departures

Next departures for Brussels to Prague on October 8
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
RegioJetBus
  • Toilet
  • Power outlets
Brussels South (Gare du Midi)
FlorencCheapestFastest

Last refresh of the prices: Today at 5:23 AM CEST.

Compare 2 ways to go from Brussels to Prague

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 18 hours 35 minutes and with fares starting at just ARS 39,907, it presents an excellent value for a comfortable ride.

36bus per day
18h 35mAverage Duration
442 milesDistance
18kgCO₂ emissions
Bus
Average PriceARS 39,907 - ARS 325,069Average Duration18h 35m
18kg CO₂e
Train
Average PriceARS 164,069 - ARS 436,656Average Duration16h 48m
17kg CO₂e

Frequently asked questions about traveling from Brussels to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Brussels to Prague?

    The cheapest bus tickets from Brussels to Prague start from ARS 39,907. The average price for this route is around ARS 104,638. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Brussels to Prague?

    The average bus trip duration from Brussels to Prague is 18h 35m, covering a distance of 442 miles (713 km). The quickest bus can get you there in 11h 55m and is operated by RegioJet.

  3. Which bus companies service the Brussels to Prague route?

    Several major bus companies operate on this route with 36 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.

  4. What is the earliest and latest departure time for the bus from Brussels to Prague?

    The earliest bus departs from Brussels to Prague at 12:45am. And the latest bus departs at 10:55pm.

  5. What are the CO₂ emissions for the bus trip from Brussels to Prague?

    A bus trip from Brussels to Prague generates an estimated 17.8137 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Brussels to Prague?

    According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1112 reviews.

  7. Which bus company has the best Wi-Fi from Brussels to Prague?

    Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.7.

  8. Which bus company has the most timely service from Brussels to Prague?

    According to Busbud traveler reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Brussels to Prague?

    According to Busbud traveler reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/04
ARS 90,800
10/05
ARS 111,447
Today
ARS 91,346
10/07
No data
10/08
ARS 71,743
10/09
ARS 101,615
10/10
ARS 95,818
10/11
ARS 89,413
busbud logoThe cheapest trip from Brussels to Prague was searched and found on Oct 8, 2026 with a price of ARS 71,743

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Prague, as early as possible.

You can expect to pay from ARS 71,743 to ARS 259,762 for a bus ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 71,743 which is on 2026-10-08.

What's the cheapest way to go from Brussels to Prague?

busbud logoThe Bus is the cheapest travel choice for this destination

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