Next departures for Brussels to Prague on August 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels North Train Station
PRG Airport
Cheapest
Bus
Brussels South (Gare du Midi)
Prague (Central Bus Station Florenc)
Fastest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Station - parking)
No tags
Bus
Brussels North Train Station
Prague (Main Station - parking)
No tags
Bus
Brussels South (Gare du Midi)
Černý Most
No tags
Bus
Brussels North Train Station
PRG Airport
No tags
Next departures for Brussels to Prague on August 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels-South (Gare du Midi)
Florenc
CheapestFastest
Bus
Brussels North Train Station
Florenc
No tags
Next departures for Brussels to Prague on August 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels North Train Station
Prague (Main Railway Station)
Cheapest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
Fastest
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Central Bus Station Florenc)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Railway Station)
No tags
Bus
Brussels North Train Station
Prague (Main Station - parking)
No tags
Next departures for Brussels to Prague on August 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels South (Gare du Midi)
Florenc
CheapestFastest
Next departures for Brussels to Prague on August 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brussels-South (Gare du Midi)
Florenc
CheapestFastest
Bus
Brussels North Train Station
Florenc
No tags
Last refresh of the prices: Today at 7:05 AM CEST.
Compare 2 ways to go from Brussels to Prague
We recommend taking the train
Among the sustainable travel choices, the Train stands out as a good way to reach Prague. The journey takes about 15 hours 29 minutes and with fares starting at just DKK 780, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 12626 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at DKK 422
Based on 1103 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the departure location and the ticket access but often complained with the wifi. RegioJet ticket prices on this trip start at DKK 294
RegioJet Brussels Prague recent customer reviews
RegioJet is the best bus
Every Thing was nice
Very good
Frequently asked questions about traveling from Brussels to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Brussels to Prague?
The cheapest bus tickets from Brussels to Prague start from DKK 225. The average price for this route is around DKK 719. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brussels to Prague?
The average bus trip duration from Brussels to Prague is 18h 30m, covering a distance of 442 miles (713 km). The quickest bus can get you there in 11h 55m and is operated by RegioJet.
Which bus companies service the Brussels to Prague route?
Several major bus companies operate on this route with 43 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.
What is the earliest and latest departure time for the bus from Brussels to Prague?
The earliest bus departs from Brussels to Prague at 12:45am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Brussels to Prague?
A bus trip from Brussels to Prague generates an estimated 17.808125 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Brussels to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1102 reviews.
Which bus company has the best Wi-Fi from Brussels to Prague?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Brussels to Prague?
According to Busbud traveler reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from Brussels to Prague?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/16
DKK 469
08/17
DKK 598
Today
DKK 526
08/19
No data
08/20
DKK 388
08/21
DKK 440
08/22
DKK 542
08/23
DKK 471
The cheapest trip from Brussels to Prague was searched and found on Aug 20, 2026 with a price of DKK 388
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Prague, as early as possible.
You can expect to pay from DKK 388 to DKK 1,025 for a bus ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at DKK 388 which is on 2026-08-20.
The cheapest trip from Brussels to Prague was searched and found on Aug 20, 2026 with a price of DKK 388
