How much is the bus ticket from Brussels to Prague?

The cheapest bus tickets from Brussels to Prague start from CLP 40,060. The average price for this route is around CLP 76,787. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Brussels to Prague?

The average bus trip duration from Brussels to Prague is 18h 50m, covering a distance of 442 miles (713 km). The quickest bus can get you there in 11h 55m and is operated by RegioJet .

Which bus companies service the Brussels to Prague route?

Several major bus companies operate on this route with 30 buses available per day, including services from FlixBus , BlaBlaCar Bus , RegioJet , Musil Tour .

What is the earliest and latest departure time for the bus from Brussels to Prague?

The earliest bus departs from Brussels to Prague at 12:45am. And the latest bus departs at 10:55pm.

What are the CO₂ emissions for the bus trip from Brussels to Prague?

A bus trip from Brussels to Prague generates an estimated 17.81765 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Brussels to Prague?

According to Busbud customers, the highest-rated bus company on this route is RegioJet , with an average rating of 4.1 out of 5 stars based on 1074 reviews.

Which bus company has the best Wi-Fi from Brussels to Prague?

Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

Which bus company has the most timely service from Brussels to Prague?

According to Busbud traveler reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 4.0 out of 5 stars.

Which bus company has the cleanest buses from Brussels to Prague?

According to Busbud traveler reviews, the bus company with the cleanest buses on this route is RegioJet , with a cleanliness rating of 4.4 out of 5 stars.

Bus Brussels to Prague from CLP 43,850 | Refundable Tickets

Next bus departures

Next departures for Brussels to Prague on May 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	6:30pm	Brussels South (Gare du Midi)	11h 55m	6:25am	Florenc	CheapestFastest

Next departures for Brussels to Prague on May 11
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	5:35pm	Brussels-South (Gare du Midi)	16h 10m	9:45am	Florenc	Cheapest
Bus	9:30am	Brussels North Train Station	12h 50m	10:20pm	Prague (Central Bus Station Florenc)	Fastest
Bus	3:55pm	Brussels North Train Station	15h	6:55am	Prague (Central Bus Station Florenc)	No tags
Bus	6:30pm	Brussels North Train Station	14h 50m	9:20am	Prague (Central Bus Station Florenc)	No tags
Bus	9:30pm	Brussels North Train Station	15h 40m	1:10pm	Prague (Central Bus Station Florenc)	No tags

Next departures for Brussels to Prague on May 13
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	3:15am	Brussels South (Gare du Midi)	20h 10m	11:25pm	PRG Airport	Cheapest
Bus	9:30am	Brussels North Train Station	12h 50m	10:20pm	Prague (Central Bus Station Florenc)	Fastest
Bus	3:55pm	Brussels North Train Station	15h	6:55am	Prague (Central Bus Station Florenc)	No tags
Bus	6:30pm	Brussels North Train Station	14h 50m	9:20am	Prague (Central Bus Station Florenc)	No tags
Bus	9:30pm	Brussels North Train Station	15h 10m	12:40pm	Prague (Central Bus Station Florenc)	No tags

Next departures for Brussels to Prague on May 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	6:30pm	Brussels South (Gare du Midi)	11h 55m	6:25am	Florenc	CheapestFastest

Next departures for Brussels to Prague on May 15
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	5:35pm	Brussels-South (Gare du Midi)	16h 10m	9:45am	Florenc	Cheapest
Bus	9:30am	Brussels North Train Station	12h 50m	10:20pm	Prague (Central Bus Station Florenc)	Fastest
Bus	3:55pm	Brussels North Train Station	15h	6:55am	Prague (Central Bus Station Florenc)	No tags
Bus	6:30pm	Brussels North Train Station	14h 50m	9:20am	Prague (Central Bus Station Florenc)	No tags
Bus	9:30pm	Brussels North Train Station	15h 10m	12:40pm	Prague (Central Bus Station Florenc)	No tags

Last refresh of the prices: Yesterday at 11:18 PM CEST.

Compare 2 ways to go from Brussels to Prague

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Prague. The journey takes about 15 hours 13 minutes and with fares starting at just CLP 78,385, it presents an excellent value for a comfortable ride.

1train per day

15h 13mAverage Duration

446 milesDistance

17kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceCLP 40,060 - CLP 237,053	Average Duration18h 50m	CO₂ emissions 18kg CO₂e
Train	Average PriceCLP 78,385 - CLP 396,744	Average Duration15h 13m	CO₂ emissions 17kg CO₂e

Where are the popular stops in Brussels and Prague?

Stops in Brussels

A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium
Visit page
B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
Visit page
C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
D
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Visit page

Stops in Prague

A
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page
B
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page
C
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page
D
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
E
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Compare companies

FlixBus

3.5/512,608 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

BlaBlaCar Bus

3.7/511,752 reviews

Staff4.4

Timeliness3.6

Cleanliness4.3

Wifi2.6

RegioJet

4.1/51,074 reviews

Staff4.5

Timeliness3.9

Cleanliness4.4

Wifi3.8

Musil Tour

CZ bus companies:FlixBus, BlaBlaCar Bus, ALSA, Rede Expressos, Sindbad, BlaBlaCar Bus - Alsa, RegioJet

Frequently asked questions about traveling from Brussels to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Brussels to Prague?
The cheapest bus tickets from Brussels to Prague start from CLP 40,060. The average price for this route is around CLP 76,787. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brussels to Prague?
The average bus trip duration from Brussels to Prague is 18h 50m, covering a distance of 442 miles (713 km). The quickest bus can get you there in 11h 55m and is operated by RegioJet.
Which bus companies service the Brussels to Prague route?
Several major bus companies operate on this route with 30 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet, Musil Tour.
What is the earliest and latest departure time for the bus from Brussels to Prague?
The earliest bus departs from Brussels to Prague at 12:45am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Brussels to Prague?
A bus trip from Brussels to Prague generates an estimated 17.81765 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Brussels to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1074 reviews.
Which bus company has the best Wi-Fi from Brussels to Prague?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Brussels to Prague?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Brussels to Prague?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/08

CLP 61,638

05/09

CLP 69,482

Today

CLP 77,125

05/11

CLP 55,145

05/12

No data

05/13

CLP 81,070

05/14

CLP 54,789

05/15

CLP 59,565

The cheapest trip from Brussels to Prague was searched and found on May 14, 2026 with a price of CLP 54,789

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Prague, as early as possible.

You can expect to pay from CLP 54,789 to CLP 192,510 for a bus ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 54,789 which is on 2026-05-14.