Bus Tickets from Brussels to Prague

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TodayMay 16
from $69
TomorrowMay 17
from $71
SunMay 18
from $67
MonMay 19
from $55
TueMay 20
from $52
WedMay 21
from $52
ThuMay 22
from $52
FriMay 23
from $58

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 17 at
    Departure city: Brussels
    Departure location: Brussels South (Gare du Midi)
    Arrival time: May 18 at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 17 at
    Departure city: Brussels
    Departure location: Brussels-North (Gare du Nord)
    Arrival time: May 18 at
    Destination city: Prague
    Destination location: Prague (Na Knížecí)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: May 17 at
    Departure city: Brussels
    Departure location: Brussels-South (Gare du Midi)
    Arrival time: May 17 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: May 17 at
    Departure city: Brussels
    Departure location: Brussels-North (Gare du Nord)
    Arrival time: May 17 at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: May 17 at
    Departure city: Brussels
    Departure location: Brussels-North (Gare du Nord)
    Arrival time: May 18 at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Accepted payments

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Compare 2 ways to go from Brussels to Prague.

Average Price$32 - $258Average Duration19h 15m
18kg CO₂e5 out of 5 stars
Cheapest
Average Price$90 - $350Average Duration13h 1m
17kg CO₂e5 out of 5 stars
FastestMost eco-friendly
busbud logoBusbud recommends taking the train from Brussels to Prague

Among the sustainable travel choices, the train stands out as the good way to reach Prague. The journey takes about 13 hours 1 minute and with fares starting at just $90, it presents an excellent value for a comfortable ride.

3train per day
13h 1mAverage Duration
$90Cheapest ticket
17kgCO₂ emissions

Bus Brussels to Prague: Trip Overview

Average ticket price$83
Average bus trip duration19h 15m
Number of daily buses35
Earliest bus departure12:45am
Distance446 miles (718 km)
Latest bus departure11:30pm

Brussels to Prague Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Brussels to Prague.

Bus service from Brussels to Prague will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Brussels to Prague, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Brussels - Prague

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/14
$65
05/15
$62
Today
$69
05/17
$72
05/18
$67
05/19
$56
05/20
$52
05/21
$52
busbud logoThe cheapest trip from Brussels to Prague was searched and found on May 21, 2025 with a price of $52

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Prague, as early as possible.

You can expect to pay from $52 to $167 for a bus ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2025-05-21.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Brussels to Prague but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Brussels to Prague, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Brussels to Prague that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Brussels to Prague, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Brussels to Prague?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Brussels by bus?

Bus from Brussels to Prague

You can also go to Prague by train

Train from Brussels to Prague

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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