Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Niagara Frontier Transportation Authority | Downtown Greyhound Station | CheapestFastest | ||||
| Bus | Niagara Frontier Transportation Authority | 537-517 W. Jackson Blvd | No tags | ||||
| Bus | Niagara Frontier Transportation Authority | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Today at 12:22 AM EST.
Compare 2 ways to travel from Buffalo to Chicago
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 16 hours 40 minutes and with fares starting at just R 985, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Chicago?
Stops in Buffalo
- A
Buffalo Airport
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- B
Chicago O'Hare International Airport
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Frequently asked questions about travelling from Buffalo, NY to Chicago by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Buffalo to Chicago?
The cheapest bus tickets from Buffalo to Chicago start at R 985. The average price for this route is around R 1 567. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Buffalo to Chicago?
The average bus journey time from Buffalo to Chicago is 16h 40m, covering a distance of 729 km. The fastest bus gets you there in 13h 10m and is operated by Greyhound.
Which bus companies service the Buffalo to Chicago route?
What is the earliest and latest departure time for the bus from Buffalo to Chicago?
The earliest bus departs from Buffalo to Chicago at 07:55. And the latest bus departs at 07:55.
What are the CO₂ emissions for the bus trip from Buffalo to Chicago?
A bus trip from Buffalo to Chicago produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Buffalo to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Buffalo to Chicago?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Buffalo to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Chicago was searched and found on 18 Dec 2025 with a price of R 1 430To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Chicago as early as possible.
You can expect to pay from R 1 430 to R 3 324 for a bus ticket from Buffalo, NY to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 430, which is on 2025-12-18.
What's the cheapest way to go from Buffalo, NY to Chicago?
The bus is the cheapest travel choice for this destination
