Bus Tickets from Buffalo, NY to Chicago, IL

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TueMay 13
from US$67
WedMay 14
from US$67
ThuMay 15
FriMay 16
SatMay 17
SunMay 18
MonMay 19
TueMay 20

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 14 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: May 15 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 14 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: May 14 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: May 14 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: May 15 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: May 15 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 11:07 AM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Buffalo to Chicago

Bus
Average PriceUS$56 - US$149Average Duration18h 20m
18kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$88 - US$192Average Duration10h 33m
67kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Buffalo to Chicago

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 18 hours 20 minutes, and with fares starting at just US$56, it presents an excellent value for a comfortable ride.

5bus per day
18h 20mAverage Duration
US$56Cheapest ticket
18kgCO₂ emissions

Bus Buffalo to Chicago: Trip Overview

Average Ticket PriceUS$76
Average Bus Trip Duration18h 20m
Number of daily buses5
Earliest bus departure7:55am
Distance729 km
Latest bus departure10:45pm

Buffalo to Chicago Bus

Busbud helps you find a bus from Buffalo to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Buffalo to Chicago from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Buffalo to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Buffalo - Chicago

  1. How long is the trip from Buffalo to Chicago by bus?

    The typical travel time from Buffalo to Chicago by bus is around 18h 20m. The fastest bus on this trip will get to Chicago in 13h 10m

  2. What is the travel distance from Buffalo to Chicago?

    The distance covered from Buffalo to Chicago is 731 km (453 miles).

  3. What are the departure and arrival locations for buses traveling from Buffalo to Chicago?

    Buses traveling this route start their trip at Buffalo Airport, in Buffalo, and end it at Downtown Greyhound Station, in Chicago.

  4. What is the cheapest way to go from Buffalo to Chicago?

    Taking the bus is the cheapest option to travel from Buffalo to Chicago. With a starting ticket price of US$56, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from Buffalo to Chicago?

    The bus fare from Buffalo to Chicago is approximately US$76.

  6. Is there an overnight bus from Buffalo to Chicago?

    Yes! Catch buses leaving from Buffalo until 10:45pm and reaching Chicago on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-09
US$97
05-10
US$91
Today
US$82
05-12
No data
05-13
US$59
05-14
US$62
05-15
US$59
05-16
US$62
busbud logoThe cheapest trip from Buffalo to Chicago was searched and found on May 13, 2025 with a price of US$59

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo to Chicago, as early as possible.

You can expect to pay from US$59 to US$98 for a bus ticket from Buffalo to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$59 which is on 2025-05-13.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Buffalo and Chicago!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Buffalo to Chicago, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Buffalo to Chicago that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Buffalo to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Buffalo to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Buffalo by bus?

Bus from Buffalo to Chicago

You can also go to Chicago by train

Train from Buffalo to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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