Next departures from Buffalo to Chicago on 22 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Niagara Frontier Transportation Authority
537-517 W. Jackson Blvd
Cheapest
Bus
Niagara Frontier Transportation Authority
Downtown Greyhound Station
Fastest
Bus
Niagara Frontier Transportation Authority
Chicago 95Th & Dan Ryan
No tags
Next departures from Buffalo to Chicago on 23 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Niagara Frontier Transportation Authority
Downtown Greyhound Station
CheapestFastest
Bus
Niagara Frontier Transportation Authority
537-517 W. Jackson Blvd
No tags
Bus
Niagara Frontier Transportation Authority
Chicago 95Th & Dan Ryan
No tags
Next departures from Buffalo to Chicago on 25 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Niagara Frontier Transportation Authority
Downtown Greyhound Station
CheapestFastest
Bus
Niagara Frontier Transportation Authority
537-517 W. Jackson Blvd
No tags
Bus
Niagara Frontier Transportation Authority
Chicago 95Th & Dan Ryan
No tags
Next departures from Buffalo to Chicago on 26 November
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Niagara Frontier Transportation Authority
537-517 W. Jackson Blvd
Cheapest
Bus
Niagara Frontier Transportation Authority
Downtown Greyhound Station
Fastest
Bus
Niagara Frontier Transportation Authority
Chicago 95Th & Dan Ryan
No tags
Last refresh of the prices: Today at 09:09 EST.
Compare 2 ways to travel from Buffalo to Chicago
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 15 hours 30 minutes and with fares starting at just £44, it presents an excellent value for a comfortable ride.
Based on 13 reviews, Greyhound was rated 2.4 stars for this trip. Greyhound ticket prices on this trip start at £44, with the trip lasting on average 992.
Greyhound Buffalo Chicago recent customer reviews
Very unhappy with our travel from Buffalo to Chicago. The bus from buffalo to cleavelent was an hour late which was not the the biggest drama however the problem was that the greyhound bus station in both buffalo and cleavelend was very miserable, cold, dirty and smelly and most of all looking very unsafe. The whole experience really made us not want to travel with a bus anymore in our life.
1 out of 5 stars
Pamela D.
Before was good but yesterday i was shocked because i could not move back of my seat .most of the seat greyhound should fixed
2 out of 5 stars
Mostafa S.
I am dissatisfied with the services of Greyhound. Unsystematic and slow work.
Based on 11395 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at £42
Frequently asked questions about travelling by bus from Buffalo, NY to Chicago
How far is Chicago from Buffalo by coach?
The distance between Buffalo and Chicago by coach is approximately 453 miles (731 km).
Is there a way to reach Chicago from Buffalo without flying?
You have the option to select the coach for your journey on this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
19/11
£76
20/11
£81
Today
£88
22/11
£90
23/11
£127
24/11
£56
25/11
£97
26/11
£108
The cheapest trip from Buffalo, NY to Chicago was searched and found on 24 Nov 2025 with a price of £56
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Chicago as early as possible.
You can expect to pay from £56 to £193 for a bus ticket from Buffalo, NY to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £56, which is on 2025-11-24.
What's the cheapest way to go from Buffalo, NY to Chicago?
The bus is the cheapest travel choice for this destination
The cheapest trip from Buffalo, NY to Chicago was searched and found on 24 Nov 2025 with a price of £56
The bus is the cheapest travel choice for this destination
