Find coaches from Charleston, SC, US to Buffalo, NY

Previously seen journeys

Next departures from Charleston to Buffalo on 30 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
4565 Gaynor Ave, North Charleston
Niagara Frontier Transportation AuthorityNo tags
Greyhound + FlixBus
4565 Gaynor Ave, North Charleston
Niagara Frontier Transportation AuthorityNo tags
FlixBus + Greyhound
4565 Gaynor Ave, North Charleston
Niagara Frontier Transportation AuthorityNo tags
Greyhound + FlixBus
4565 Gaynor Ave, North Charleston
Niagara Frontier Transportation AuthorityNo tags
FlixBus + Greyhound
4565 Gaynor Ave, North Charleston
Buffalo (BUF) AirportNo tags

Accepted payments

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Compare 2 ways to travel from Charleston to Buffalo

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 1 day, 3 hours 55 minutes and with fares starting at just US$164, it presents an excellent value for a comfortable ride.

2bus per day
1d 3hAverage duration
1124 kmDistance
28kgCO₂ emissions
Bus
Average priceUS$164 - US$223Average duration1d 3h
28kg CO₂e
Train
Average priceUS$233 - US$470Average duration1d
102kg CO₂e

Bus Charleston, SC, US to Buffalo, NY: Trip Overview

Average ticket priceUS$177
Average bus trip duration1d 3h
Number of daily buses2
Earliest bus departure13:55
Distance1124 km
Latest bus departure15:15

Charleston to Buffalo Bus

Busbud helps you find a bus from Charleston to Buffalo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Charleston to Buffalo.

Discover how much the bus trip from Charleston to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Charleston, SC, US - Buffalo, NY

  1. How much does a bus ticket from Charleston to Buffalo cost?

    The bus ticket price from Charleston to Buffalo starts at US$164. The best way to find cheap bus tickets from Charleston to Buffalo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Charleston to Buffalo?

    The average travel time between Charleston and Buffalo is around 1d 3h, although the fastest bus will take about 1d 3h. This is the time it takes to travel the 1129 km that separates the two cities.

  3. How many daily bus connections are there between Charleston and Buffalo?

    The number of buses from Charleston to Buffalo can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Charleston to Buffalo by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Charleston to Buffalo?

    When taking the bus from Charleston to Buffalo, you can travel comfortably and safely with FlixBus, Greyhound.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
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29/10
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Today
US$169
31/10
No data
01/11
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02/11
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03/11
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04/11
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busbud logoThe cheapest trip from Charleston, SC, US to Buffalo, NY was searched and found on 30 Oct 2025 with a price of US$169

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Buffalo, NY as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Charleston and Buffalo!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Charleston to Buffalo.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Charleston to Buffalo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Charleston to Buffalo.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Charleston, SC, US to Buffalo, NY?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Charleston, SC, US by bus?

Bus from Buffalo, NY to Charleston, SC, US

You can also go to Buffalo, NY by train

Train from Charleston, SC, US to Buffalo, NY

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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