What is the travel distance from Charleston to Buffalo?

The distance separating Charleston and Buffalo is 700 miles (1129 km).

What are the departure and arrival stations when taking the bus from Charleston to Buffalo?

The majority of buses traveling from Charleston to Buffalo start their journey at Charleston Bus Station and wind up at Buffalo Airport. These are the most popular pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

Bus Charleston to Buffalo from $128 | Refundable Tickets

Next bus departures

Next departures for Charleston to Buffalo on November 12
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	11:35am	4565 Gaynor Ave, North Charleston	1d 5h	5:30pm	Buffalo (BUF) Airport	Cheapest
	Bus	11:35am	4565 Gaynor Ave, North Charleston	1d 5h	5:25pm	Niagara Frontier Transportation Authority	Fastest

Next departures for Charleston to Buffalo on November 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	11:35am	4565 Gaynor Ave, North Charleston	1d 5h	5:30pm	Buffalo (BUF) Airport	Cheapest
	Bus	11:35am	4565 Gaynor Ave, North Charleston	1d 5h	5:25pm	Niagara Frontier Transportation Authority	Fastest

Next departures for Charleston to Buffalo on November 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	11:35am	4565 Gaynor Ave, North Charleston	1d 5h	5:30pm	Buffalo (BUF) Airport	Cheapest
	Bus	11:35am	4565 Gaynor Ave, North Charleston	1d 5h	5:25pm	Niagara Frontier Transportation Authority	Fastest

Last refresh of the prices: Yesterday at 10:04 AM EST.

Compare 2 ways to go from Charleston to Buffalo

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 1 day, 3 hours 55 minutes and with fares starting at just $164, it presents an excellent value for a comfortable ride.

2bus per day

1d 3hAverage Duration

697 milesDistance

28kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$164 - $223	Average Duration1d 3h	CO₂ emissions 28kg CO₂e
Train	Average Price$233 - $470	Average Duration1d	CO₂ emissions 102kg CO₂e

Compare bus companies

FlixBus

3.5/511,279 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,367 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Charleston and Buffalo?

Stops in Charleston

A - Charleston Bus Station

Stops in Buffalo

A - Buffalo Airport

B - Transportation Center

C - Exchange Street Station

Frequently asked questions about traveling from Charleston, SC, US to Buffalo, NY by bus

What is the travel distance from Charleston to Buffalo?
What are the departure and arrival stations when taking the bus from Charleston to Buffalo?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/09

No data

11/10

$146

Today

$204

11/12

$128

11/13

$128

11/14

$128

11/15

No data

11/16

No data

The cheapest trip from Charleston, SC, US to Buffalo, NY was searched and found on Nov 12, 2025 with a price of $128

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Buffalo, NY, as early as possible.

You can expect to pay from $128 to $204 for a bus ticket from Charleston, SC, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $128 which is on 2025-11-12.