Find coaches from Chicago to St. Louis

Next departures

Next departures from Chicago to St. Louis on 4 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
    		Chicago 95Th & Dan Ryan
    		Gateway StationCheapest
    Greyhound Lines, Inc.
      		Chicago 95Th & Dan Ryan
      		Gateway StationFastest
      Greyhound Lines, Inc.
        		Downtown Greyhound Station
        		Gateway StationNo tags
        Greyhound Lines, Inc.
          		Downtown Greyhound Station
          		Gateway StationNo tags
          Greyhound Lines, Inc.
            		Downtown Greyhound Station
            		Gateway StationNo tags

            Last refresh of the prices: Yesterday at 9:58 PM CST.

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            Compare 2 ways to travel from Chicago to St. Louis

            We recommend taking the train

            Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 5 hours 1 minute and with fares starting at just US$30, it presents an excellent value for a comfortable ride.

            5train per day
            5h 1mAverage duration
            423 kmDistance
            38kgCO₂ emissions
            Bus
            		Average priceUS$36 - US$182Average duration7h 55m
            10kg CO₂e
            Train
            		Average priceUS$30 - US$98Average duration5h 1m
            38kg CO₂e

            Bus Chicago to St. Louis: Trip Overview

            Average ticket priceUS$48
            Average bus trip duration7h 55m
            Number of daily buses12
            Earliest bus departure00:15
            Distance408 km
            Latest bus departure23:50

            Chicago to St. Louis Bus

            With Busbud, comparing and booking tickets for a bus from Chicago to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make sure you can find a bus service from Chicago to St. Louis from the most reliable bus companies operating this trip.

            From cheap bus tickets to more luxurious buses travelling from Chicago to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions on the trip Chicago - St. Louis

            1. How much does a bus ticket from Chicago to St. Louis cost?

              The bus ticket price from Chicago to St. Louis starts at US$36. The best way to find cheap bus tickets from Chicago to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Chicago to St. Louis?

              The average travel time between Chicago and St. Louis is around 7h 55m, although the fastest bus will take about 4h 45m. This is the time it takes to travel the 419 km that separates the two cities.

            3. How many daily bus connections are there between Chicago and St. Louis?

              The number of buses from Chicago to St. Louis can differ depending on the day of the week. On average, there are 12 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Chicago to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Chicago to St. Louis?

              When taking the bus from Chicago to St. Louis, you can travel comfortably and safely with FlixBus, Greyhound, Burlington Trailways.

            5. What are the departure and arrival stations when taking the bus from Chicago to St. Louis?

              Buses travelling between Chicago and St. Louis leave from Downtown Greyhound Station or Chicago O'Hare International Airport and arrive at Gateway Station.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            01/11
            US$52
            02/11
            US$62
            Today
            US$47
            04/11
            US$58
            05/11
            US$44
            06/11
            US$37
            07/11
            US$37
            08/11
            US$41
            busbud logoThe cheapest trip from Chicago to St. Louis was searched and found on 06 Nov 2025 with a price of US$37

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to St. Louis as early as possible.

            You can expect to pay from US$37 to US$131 for a bus ticket from Chicago to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$37, which is on 2025-11-06.

            Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while travelling from Chicago to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from Chicago to St. Louis, get comfy and count the stars.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to St. Louis that are otherwise impossible to come by with a plane.

            Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to St. Louis.

            Did you know?

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

            One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

            Will you be returning to Chicago by bus?

            Bus from St. Louis to Chicago

            You can also go to St. Louis by train

            Train from Chicago to St. Louis

            Why choose Busbud?

            The Best Way To Book Bus and Train Tickets

            Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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