Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Downtown Greyhound Station | Gateway Station | Cheapest | ||||
| Bus | Chicago 95Th & Dan Ryan | Gateway Station | Fastest | ||||
 | Bus | Downtown Greyhound Station | Gateway Station | No tags | ||||
| Bus | Downtown Greyhound Station | Gateway Station | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Gateway Station | No tags |
Last refresh of the prices: Today at 4:28 PM CDT.
Compare 2 ways to go from Chicago to St. Louis
Among the sustainable travel choices, the Train stands out as a good way to reach St. Louis. The journey takes about 5 hours 1 minute, and with fares starting at just CZK 621, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and St. Louis?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare companies
Frequently asked questions about travelling from Chicago to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to St. Louis?
The cheapest bus tickets from Chicago to St. Louis start from CZK 876. The average price for this route is around CZK 1,131. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to St. Louis?
The average bus travel time from Chicago to St. Louis is 9h, covering a distance of 415 km. The quickest bus can get you there in 4h 46m and is operated by Amtrak.
Which bus companies service the Chicago to St. Louis route?
Several major bus companies operate on this route with 13 buses available per day, including services from FlixBus, Greyhound, Burlington Trailways, Amtrak.
What are the earliest and latest departure times for the bus from Chicago to St. Louis?
The earliest bus departs from Chicago to St. Louis at 12:15am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Chicago to St. Louis?
A bus trip from Chicago to St. Louis generates an estimated 10.353674999999999 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Chicago to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from Chicago to St. Louis?
Based on Busbud reviews, the bus company Burlington Trailways has the highest Wi-Fi rating with a score of 5.0.
Which bus company has the best on-time performance from Chicago to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Chicago to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to St. Louis was searched and found on Apr 25, 2026 with a price of CZK 894To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to St. Louis, as early as possible.
You can expect to pay from CZK 894 to CZK 2,425 for a bus ticket from Chicago to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at CZK 894 which is on 2026-04-25.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
